GutLactobacillusprotects against the progression of renal damage by modulating the gut environment in rats

Expansion of Urease- and Uricase-Containing, Indole- and p-Cresol-Forming and Contraction of Short-Chain Fatty Acid-Producing Intestinal Microbiota in ESRD

(2014) Jakk Wong et al.   AMERICAN JOURNAL OF NEPHROLOGY

Rapidly expanding knowledge on the role of the gut microbiome in health and disease

(2014) M.C. Cénit et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

FSL-1 Induces MMP-9 Production through TLR-2 and NF-κB /AP-1 Signaling Pathways in Monocytic THP-1 Cells

(2014) Rasheed Ahmad et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Indoxyl Sulfate-Induced Activation of (Pro)Renin Receptor Is Involved in Expression of TGF-β1 and α-Smooth Muscle Actin in Proximal Tubular Cells

(2014) Shinichi Saito et al.   ENDOCRINOLOGY

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

The Cardiovascular Effect of the Uremic Solute Indole-3 Acetic Acid

(2014) L. Dou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Uremic Toxicity of Indoxyl Sulfate and p-Cresyl Sulfate: A Systematic Review

(2014) R. Vanholder et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Randomized Placebo-Controlled EPPIC Trials of AST-120 in CKD

(2014) G. Schulman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renoprotective effects of novel interleukin-1 receptor-associated kinase 4 inhibitor AS2444697 through anti-inflammatory action in 5/6 nephrectomized rats

(2014) Mitsuhiro Kondo et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Modulatory Effects of Vasoactive Intestinal Peptide on Intestinal Mucosal Immunity and Microbial Community of Weaned Piglets Challenged by an Enterotoxigenic Escherichia coli (K88)

(2014) Chunlan Xu et al.   PLoS One

Lactobacillus gasseri SBT2055 Induces TGF-β Expression in Dendritic Cells and Activates TLR2 Signal to Produce IgA in the Small Intestine

(2014) Fumihiko Sakai et al.   PLoS One

Oral Activated Charcoal Adsorbent (AST-120) Ameliorates Chronic Kidney Disease-Induced Intestinal Epithelial Barrier Disruption

(2013) Nosratola D. Vaziri et al.   AMERICAN JOURNAL OF NEPHROLOGY

The Gut Microbiome, Kidney Disease, and Targeted Interventions

(2013) A. Ramezani et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

p -Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase

(2013) Hiroshi Watanabe et al.   KIDNEY INTERNATIONAL

The intestinal microbiota, a leaky gut, and abnormal immunity in kidney disease

(2013) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats

(2013) Maimaiti Yisireyili et al.   LIFE SCIENCES

Uremic Plasma Impairs Barrier Function and Depletes the Tight Junction Protein Constituents of Intestinal Epithelium

(2012) Nosratola D. Vaziri et al.   AMERICAN JOURNAL OF NEPHROLOGY

Role of Urea in Intestinal Barrier Dysfunction and Disruption of Epithelial Tight Junction in Chronic Kidney Disease

(2012) Nosratola D. Vaziri et al.   AMERICAN JOURNAL OF NEPHROLOGY

Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress

(2012) Gulinuer Muteliefu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography/tandem mass spectrometry and their effects on endothelial ROS production

(2012) Yoshiharu Itoh et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

CKD impairs barrier function and alters microbial flora of the intestine

(2012) Nosratola D. Vaziri   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Absorption-promoting effects of chitosan in airway and intestinal cell lines: A comparative study

(2012) Driton Vllasaliu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Lactobacillus amylophilus D14 protects tight junction from enteropathogenic bacteria damage in Caco-2 cells

(2012) Q. Yu et al.   JOURNAL OF DAIRY SCIENCE

Chronic kidney disease alters intestinal microbial flora

(2012) Nosratola D. Vaziri et al.   KIDNEY INTERNATIONAL

Indoxyl sulfate upregulates renal expression of ICAM-1 via production of ROS and activation of NF-κB and p53 in proximal tubular cells

(2012) Hidehisa Shimizu et al.   LIFE SCIENCES

NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells

(2011) Hidehisa Shimizu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Intestinal-Renal Syndrome: Mirage or Reality?

(2011) Eberhard Ritz   BLOOD PURIFICATION

Pilot study of probiotic dietary supplementation for promoting healthy kidney function in patients with chronic kidney disease

(2010) Natarajan Ranganathan et al.   ADVANCES IN THERAPY

Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

(2010) Jurgen Karczewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

The Uremic Toxin 3-Indoxyl Sulfate Is a Potent Endogenous Agonist for the Human Aryl Hydrocarbon Receptor

(2009) Jennifer C. Schroeder et al.   BIOCHEMISTRY

Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization

(2009) Ingrid C. McCall et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy

(2008) N. Sugano et al.   KIDNEY INTERNATIONAL