Article
Radiology, Nuclear Medicine & Medical Imaging
Marcus Raudner, Markus M. Schreiner, Tom Hilbert, Tobias Kober, Michael Weber, Anna Szelenyi, Reinhard Windhager, Vladimir Juras, Siegfried Trattnig
Summary: The study evaluated GRAPPATINI, an accelerated T-2 mapping sequence that combines undersampling and model-based reconstruction to facilitate clinical implementation of T-2 mapping of the lumbar intervertebral disc. Results showed that T2 values obtained using GRAPPATINI were significantly different for normal discs compared to bulging or herniated discs, as well as discs with and without annular tears. The study concluded that GRAPPATINI can be used as a quantitative imaging biomarker to detect disc pathologies while significantly reducing acquisition time.
EUROPEAN RADIOLOGY
(2021)
Article
Multidisciplinary Sciences
Elisabeth Sartoretti, Michael Wyss, Alex Alfieri, Christoph A. Binkert, Cyril Erne, Sabine Sartoretti-Schefer, Thomas Sartoretti
Summary: This study developed and evaluated the reproducibility of an updated 6-point grading system for lumbar foraminal stenosis based on high-resolution MRI images. The system accurately describes the condition and showed good interreader agreement.
SCIENTIFIC REPORTS
(2021)
Article
Orthopedics
Haoxiang Xu, Wangqiang Wen, Zepei Zhang, Jianqiang Bai, Bowen Kou, Jun Miao
Summary: This study investigated in vivo lumbar intervertebral disc deformations during axial rotations under different load-bearing conditions. The results showed that the deformation patterns were direction-specific and level-specific, and were affected by extra weight.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Julien Galley, Reto Sutter, Christoph Germann, Florian Wanivenhaus, Daniel Nanz
Summary: Non-invasive 3D-DESS MR-imaging at 3 and 7 T successfully visualizes the cervical nerve roots within the spinal canal and has the potential to provide precise assessments of their micro-anatomy. Interobserver agreement was substantial to almost perfect, and the ICC for the number of identified rootlets was 0.80.
EUROPEAN RADIOLOGY
(2021)
Article
Clinical Neurology
Wei Yi, Jingwei Zhao, Wen Tang, Hongkun Yin, Lifeng Yu, Yaohui Wang, Wei Tian
Summary: This study developed and validated a deep learning model for detecting lumbar degenerative disease in T2-weighted MRI scans, and evaluated its performance in detecting cervical degenerative disease.
EUROPEAN SPINE JOURNAL
(2023)
Article
Biotechnology & Applied Microbiology
Xin Xi, Zhi Ling, Cong Wang, Chunya Gu, Xuqiang Zhan, Haixin Yu, Siqi Lu, Tsung-Yuan Tsai, Yan Yu, Liming Cheng
Summary: This study aimed to quantify the soft tissue artifacts (STAs) of the human lower back in three-dimensional directions and determine their effects on the calculation of lumbar joint kinematics. The results showed that STAs had different patterns and magnitudes in the anterior/posterior and proximal/distal directions, and varied during flexion and extension. The STA at the spinous process was lower than that at other locations.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Review
Orthopedics
Eleanor Shalini Daniel, Raymond Y. W. Lee, Jonathan Mark Williams
Summary: This review examines the reliability of four non-invasive modalities (VF, US, MRI, and radiography) for measuring lumbar segmental ROM. The results show excellent reliability across all methods, although VF and radiography are limited by radiation exposure while MRI is expensive. US offers a non-invasive, risk-free option, but further research is needed to determine its consistency.
JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION
(2023)
Article
Computer Science, Software Engineering
A. Beulah, T. Sree Sharmila, V. K. Pramod
Summary: An automatic diagnostic system for degenerative discs was developed and tested on sagittal MR images of 93 patients, achieving a high accuracy rate. The system can serve as a helpful second opinion tool for diagnosing degenerative discs.
Article
Radiology, Nuclear Medicine & Medical Imaging
Rafael Menezes-Reis, Carlos E. Garrido Salmon, Gustavo P. Bonugli, Debora Mazoroski, Leonor G. Savarese, Carlos Fernando P. S. Herrero, Helton L. A. Defino, Marcello Henrique Nogueira-Barbosa
Summary: The study found that a decrease in lumbar lordosis is associated with dehydration of the intervertebral disc nucleus pulposus, while low values of sacral slope, pelvic tilt, pelvic incidence, thoracic kyphosis, and spinosacral angle are related to a decrease in T2 relaxation times of the annulus fibrosus. Overall, spinopelvic parameters show a discrete association with lumbar disc composition and water content.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2021)
Review
Biotechnology & Applied Microbiology
Dongqiang Ye, Xiaole Sun, Cui Zhang, Shen Zhang, Xini Zhang, Shaobai Wang, Weijie Fu
Summary: Foot and ankle joints are crucial for human dynamic activities, and DFIS has been shown to be an effective tool for in vivo kinematic studies, with both advantages and limitations. Existing research provides valuable insights for future studies on foot and ankle biomechanics.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Engineering, Biomedical
S. Tavana, B. Davis, I. Canali, K. Scott, J. J. H. Leong, B. A. Freedman, N. Newell
Summary: Medical imaging modalities that only calculate tissue morphology cannot provide direct information about the mechanical behavior of load-bearing musculoskeletal organs. In this study, a non-invasive tool combining digital volume correlation (DVC) with clinical MRI was developed to measure displacement and strain in the human lumbar spine. The tool was used to calculate lumbar kinematics and intervertebral disc (IVD) strains in healthy subjects during lumbar extension. The results showed that the tool had a low measurement error and provided important information about the mechanics of the spine.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Medicine, General & Internal
Nils Christian Lehnen, Robert Haase, Jennifer Faber, Theodor Ruber, Hartmut Vatter, Alexander Radbruch, Frederic Carsten Schmeel
Summary: The study evaluated the diagnostic performance of a convolutional neural network on lumbar spine MRI images, demonstrating high accuracy and consistency in automatically diagnosing various degenerative changes in the lumbar spine.
Article
Multidisciplinary Sciences
Luis Becker, Lukas Schoennagel, Tim Victor Mihalache, Henryk Haffer, Friederike Schoemig, Hendrik Schmidt, Matthias Pumberger
Summary: Patients with LSTV exhibit reduced range of motion in the transitional segment and significantly increased motion distribution to the cranial adjacent segment in flexion-extension radiographs. These findings may explain the higher rates of degeneration within the segment.
Article
Clinical Neurology
Tim Finkenstaedt, Palanan Siriwananrangsun, Koichi Masuda, Graeme M. M. Bydder, Karen C. C. Chen, Won C. C. Bae
Summary: Using UTE MRI, the study determined the prevalence of abnormal CEP and its association with disc degeneration in human lumbar spines. The results showed a 33% prevalence of CEP abnormality, which tended to increase with older age and lower spinal levels of L5. There was a significant association between abnormal CEPs and disc degeneration.
EUROPEAN SPINE JOURNAL
(2023)
Article
Medicine, General & Internal
Ralph Laeubli, Robin Brugger, Tatiana Pirvu, Sven Hoppe, Dominik Sieron, Karol Szyluk, Christoph E. Albers, Andreas Christe
Summary: This study found that the presence of disproportionate motion segments in the lower spine may lead to a significantly higher risk for disc herniation in patients undergoing discectomy.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Neurosciences
Wenjin Wang, TsungYuan Tsai, Fei Tian, Jixin Li, Yaqi Zhao, Renkun Zhu, Junjie Li, Yu Liu, Shaobai Wang
Summary: This study used high-speed fluoroscopy and MRI techniques to investigate the kinematics of healthy knees before and after marathon running. The results showed changes in knee kinematics post-marathon such as increased valgus and external femoral rotation, knee flexion, posterior femoral translation, and decreased proximal-distal distance, which may increase the risk of knee injury.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ming Zhang, Yufei Li, Ruimin Feng, Zhongzheng Wang, Wenjin Wang, Nan Zheng, Shaobai Wang, Fuhua Yan, Yong Lu, Tsung-Yuan Tsai, Hongjiang Wei
Summary: The study investigated the ability of QSM to assess microstructural changes in knee cartilage after repetitive loading, revealing a significant increase in susceptibility value in the weight-bearing region without significant changes in cartilage thickness. Furthermore, a positive correlation was found between changes in susceptibility value and knee joint motion.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Orthopedics
Shaobai Wang, Xiaolong Zeng, Liang Huangfu, Zhenyan Xie, Limin Ma, Wenhan Huang, Yu Zhang
Summary: The study validated the accuracy of the Opti_Knee system in tracking the 6DOF motion of the knee joint through comparison with a biplanar fluoroscopy system. Results showed acceptable accuracy and strong correlation strength, indicating the potential of Opti_Knee as a portable clinical system for dynamic functional assessments of the knee.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Review
Biotechnology & Applied Microbiology
Dongqiang Ye, Xiaole Sun, Cui Zhang, Shen Zhang, Xini Zhang, Shaobai Wang, Weijie Fu
Summary: Foot and ankle joints are crucial for human dynamic activities, and DFIS has been shown to be an effective tool for in vivo kinematic studies, with both advantages and limitations. Existing research provides valuable insights for future studies on foot and ankle biomechanics.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Orthopedics
Ling Zhang, Shao-bai Wang, Shuai Fan, Jiling Ye, Bin Cai
Summary: The study aimed to evaluate the difference in patellofemoral kinematics between weightbearing and non-weightbearing conditions in arthrofibrotic knees after ACL reconstruction. The results showed that patellofemoral kinematics during non-weightbearing positions do not sufficiently represent the patellar tracking during functional weightbearing activities.
INTERNATIONAL ORTHOPAEDICS
(2022)
Article
Rehabilitation
Ling Zhang, Shao-Bai Wang, Shuai Fan, Jiling Ye, Bin Cai
Summary: This study examined patellofemoral kinematics and knee extensor strength in patients with arthrofibrosis after ACL reconstruction. The findings showed decreased patellar mobility and a strong correlation between knee extensor strength and patellar inferior shift in the affected knee. High sensitivity but low specificity was observed in using knee extensor strength to identify limited patellar inferior shift in these patients.
JOURNAL OF SPORT REHABILITATION
(2021)
Article
Clinical Neurology
Benyu Tang, Haoqun Yao, Shaobai Wang, Yanlong Zhong, Kai Cao, Zongmiao Wan
Summary: This study successfully demonstrated the three-dimensional intervertebral motion characteristics of the cervical spine in healthy volunteers using CBCT combined with 3D-3D registration technology. Different segments of the cervical spine showed varying ranges of motion and coupled movements in different directions. These findings are important for the diagnosis of cervical spinal diseases, development of new surgical techniques, and restoration of normal cervical segmental movement.
Article
Multidisciplinary Sciences
Zongmiao Wan, Wenjin Wang, Chao Li, Junjie Li, Jinpeng Lin, Fei Tian, Ting Zhu, Danni Wu, Luqi Guo, Shaobai Wang
Summary: This study validates the accuracy of CBCT cervical spine modeling with 3D-3D registration for in vivo measurements of cervical spine kinematics. Results show that CBCT models have small deviations compared to CT models, demonstrating that CBCT technology can be used to measure cervical spine kinematics data.
SCIENTIFIC REPORTS
(2021)
Article
Orthopedics
Qiong Wu, Yuanzhi Zhang, Shaobai Wang, Rui Liu, Gang Liu
Summary: This study evaluates the biomechanical performance of sacroiliac screw fixation on the first sacral vertebra using different lengths of screws through the finite-element method. The results suggest that a 130-mm screw length can decrease stress concentration and effectively transfer stress, with the smallest displacement among the considered screws.
INDIAN JOURNAL OF ORTHOPAEDICS
(2022)
Article
Rehabilitation
Fei Tian, Yaqi Zhao, Jixin Li, Wenjin Wang, Danni Wu, Qiang Li, Liyun Guo, Shaobai Wang
Summary: This study evaluated the test-retest reliability of a new device and a long-arm goniometer for assessing knee joint position sense, with results showing that the new device exhibited better reliability and precision compared to the goniometer, making it a better alternative for evaluating knee proprioception.
JOURNAL OF SPORT REHABILITATION
(2022)
Article
Biotechnology & Applied Microbiology
Faning Zhang, Dongqiang Ye, Xini Zhang, Xiaole Sun, Shen Zhang, Shaobai Wang, Weijie Fu
Summary: The study investigated the differences in the six-degree-of-freedom (6DOF) kinematics of the first metatarsophalangeal joint (MTPJ) between shod and barefoot running. The results showed that wearing shoes limited the flexion and extension movement of the first MTPJ and increased the adduction angle, potentially increasing the risk of hallux valgus.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Orthopedics
Ting Zhu, Ya Wang, Fei Tian, Wenjin Wang, Rongzhou Zhong, Hua Zhai, Shaobai Wang
Summary: Patients with trimalleolar fractures show physical impairments of the ankle and altered gait parameters in the short-term.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Neurosciences
Wenjin Wang, Tsung-Yuan Tsai, Cui Zhang, Jinpeng Lin, Wei Dai, Ming Zhang, Wolfgang Potthast, Yu Liu, Shaobai Wang
Summary: This study utilized a high-speed dual fluoroscopic imaging system and magnetic resonance imaging technique to investigate the kinematics of the knee joint during walking and running. The results showed increased knee flexion, external femoral rotation, and proximal-distal distance during running compared to walking. The study provides important insights into the intrinsic biomechanics of the knee joint during gait.
Meeting Abstract
Sport Sciences
Zhang Cui, Liu Yu, Wang Shaobai
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2021)
Article
Mathematical & Computational Biology
Won Man Park, Young Joon Kim, Shaobai Wang, Yoon Hyuk Kim, Guoan Li
MATHEMATICAL BIOSCIENCES AND ENGINEERING
(2020)
Article
Biophysics
Nathan D. Camarillo, Rafael Jimenez-Silva, Frances T. Sheehan
Summary: This article discusses the statistical dependence between multiple measurements from the same participant and provides recommendations for using these measurements when they are not independent.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
J. Huet, A. -S. Boureau, A. Sarcher, C. Cornu, A. Nordez
Summary: Standard compression in freehand 3D ultrasound induces a bias in volume calculations, but minimal compression and gel pad methods have similar results. With a trained examiner and precautions, the bias can be minimized and become acceptable in clinical applications.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
C. Lariviere, A. H. Eskandari, H. Mecheri, F. Ghezelbash, D. Gagnon, A. Shirazi-Adl
Summary: Recent developments in musculoskeletal modeling have focused on model customization. Personalization of the spine profile may affect estimates of spinal loading and stability. This study investigates the biomechanical consequences of changes in the spinal profile and finds that personalizing the spine profile has medium to large effects on trunk muscle forces and negligible to small effects on spinal loading and stability.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Luke T. Mattar, Arash B. Mahboobin, Adam J. Popchak, William J. Anderst, Volker Musahl, James J. Irrgang, Richard E. Debski
Summary: Exercise therapy fails in about 25.0% of cases for individuals with rotator cuff tears, and one reason for this failure may be the inability to strengthen and balance the muscle forces that keep the humeral head in the correct position. This study developed computational musculoskeletal models to compare the net muscle force before and after exercise therapy between successfully and unsuccessfully treated patients. The study found that unsuccessfully treated patients had less inferiorly oriented net muscle forces, which may increase the risk of impingement.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Natsuki Sado, Takeshi Edagawa, Toshihide Fujimori, Shogo Hashimoto, Yoshikazu Okamoto, Takahito Nakajima
Summary: The existing methods for predicting hip and lumbosacral joint centres in Japanese adults are biased and differ between sexes. We propose new regression equations that consider soft-tissue thickness, sex differences, and a height-directional measure, and validate them using leave-one-out cross-validation.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Peimin Yu, Xuanzhen Cen, Qichang Mei, Alan Wang, Yaodong Gu, Justin Fernandez
Summary: This study aimed to explore the intra-foot biomechanical differences among individuals with chronic ankle instability (CAI), copers, and healthy individuals during dynamic tasks. The study found that copers and CAI individuals had smaller dorsiflexion angles and copers presented a more eversion position compared to healthy participants. Copers also had greater dorsiflexion angles in the metatarsophalangeal joint and more inversion moments in the subtalar joint during certain tasks. These findings can help in designing interventions to restore ankle joint functions in CAI individuals.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Jon Skovgaard Jensen, Anders Holsgaard-Larsen, Anders Stengaard Sorensen, Per Aagaard, Jens Bojsen-Moller
Summary: This study investigates the biomechanical effects of robot-assisted body weight unloading (BWU) on gait patterns in healthy young adults. The results show that dynamic robot-assisted BWU enables reduced kinetic requirements without distorting biomechanically normal gait patterns during overground walking.
JOURNAL OF BIOMECHANICS
(2024)