Article
Engineering, Biomedical
Andrew Y. W. Wong, Amanda Farias Zuniga, Peter J. Keir
Summary: This study aimed to investigate the effects of blood flow occlusion and sex-specific differences in tendon-subsynovial connective tissue relative strain. The results showed that occlusion and fast movement speed reduced the displacement of flexor digitorum superficialis tendon and subsynovial connective tissue. Movement speed also had a significant effect on tendon-subsynovial connective tissue shear outcomes. These findings provide insights into the pathophysiology of carpal tunnel syndrome and the motion of carpal tunnel tissue when the local fluid environment is disturbed.
CLINICAL BIOMECHANICS
(2023)
Article
Engineering, Biomedical
Mohammad Hosseini-Farid, Verena J. M. M. Schrier, Julia Starlinger, Chunfeng Zhao, Peter C. Amadio
Summary: This study found that the relative movement of subsynovial tissue increases in patients with carpal tunnel syndrome after intervention, especially in those with mild disease severity undergoing surgery.
CLINICAL BIOMECHANICS
(2021)
Article
Orthopedics
Amanda Farias Zuniga, Amer A. Ghavanini, Gaspar Israelian, Peter J. Keir
Summary: The study found that ultrasound measurements can be used as an effective tool to predict changes in nerve function in CTS patients.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2021)
Article
Engineering, Biomedical
Antonion Korcari, Mark R. Buckley, Alayna E. Loiselle
Summary: This study focuses on characterizing the mechanical properties of scar tissue and comparing them with the properties of the composite healing tissues in flexor digitorum longus tendons. The method used in the study identifies significant differences between the scar tissue and the composite tissues, suggesting that testing composite healing tendons without isolating the scar tissue overestimates the material properties of the scar itself. The study also validates the experimental findings with the help of inverse finite element analysis.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Medicine, General & Internal
Kyoko Muneshige, Kenji Onuma, Koji Sukegawa, Yuya Otake, Gen Inoue, Masashi Takaso, Kentaro Uchida
Summary: This study found that COL5A1 expression is elevated in patients undergoing hemodialysis and that B2-MG may regulate its expression, suggesting a potential mechanism for the development of carpal tunnel syndrome in these patients.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Engineering, Multidisciplinary
Rong Bao, Shi Cheng, Jianyu Zhu, Feng Hai, Wenli Mi, Shen Liu
Summary: This study aims to create a simplified model for tendon adhesion without sutures in the murine flexor tendon. The experimental results show that this model can mimic classical tendon repair models without significant side effects on biomechanics.
Article
Orthopedics
Chien-Ting Liu, Dung-Huan Liu, Chii-Jen Chen, You-Wei Wang, Pao-Sheng Wu, Yi-Shiung Horng
Summary: Reduced gliding ability of the median nerve was observed in patients with CTS, with a lower ratio of median nerve excursion to flexor tendon excursion compared to healthy volunteers. Wrist extension to 30 degrees increased median nerve excursion in CTS patients, suggesting it may be beneficial for improving median nerve mobilization in CTS patients.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Engineering, Biomedical
Julian Sartori, Heiko Stark
Summary: This study analyzed the 3D fiber tracks in macroscopic tendon samples, revealing that the insertion is not reinforced in terms of fiber numbers or sizes. The orientation of fibers in the tendon center is higher than in the margins, which could inspire material development. Fibers inserting at a protrusion of the insertion area stem from a distinct portion within the tendon, suggesting that fibrous structure analysis can link macro- to micromechanics.
ACTA BIOMATERIALIA
(2021)
Article
Acoustics
Amanda Farias Zuniga, Peter J. Keir
Summary: There is evidence supporting the vascular hypothesis of carpal tunnel syndrome (CTS) development, indicating the role of ischemia and edema in driving the condition. This study aimed to investigate the temporal effects of sub-diastolic brachial blood flow occlusion on various parameters related to CTS, including nerve function, tissue mechanics, and stiffness. The results demonstrated the significant impact of partial ischemia on nerve conduction, tendon-connective tissue displacement, and shear strain, highlighting the importance of adequate blood flow for carpal tunnel tissue function.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2022)
Article
Surgery
S. Tullie, A. Wiberg, D. Furniss, A. Schmid
Summary: This pilot study used MRI to assess sub-synovial connective tissues (SSCT) in patients with carpal tunnel syndrome (CTS). The study found decreased SSCT signal intensity and decreased wrist index in the distal carpal tunnel of CTS patients, which were normalized after surgery. These preliminary findings warrant further investigation in a larger cohort.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Article
Biophysics
Yoichi Toyoshima, Boran Zhou, Kazutoshi Kubo, Kai-Nan An, Steven L. Moran, Xiaoming Zhang, Peter C. Amadio, Chunfeng Zhao
Summary: The study investigated the feasibility of using noninvasive ultrasound vibro-elastography to predict carpal tunnel pressure in patients with carpal tunnel syndrome. Results showed that measuring the shear wave speed ratio could indirectly estimate the carpal tunnel pressure, making it potentially useful for the early diagnosis and assessment of CTS.
JOURNAL OF BIOMECHANICS
(2021)
Article
Engineering, Biomedical
Jacqueline Solis-Cordova, Jennifer H. Edwards, Hazel L. Fermor, Philip Riches, Claire L. Brockett, Anthony Herbert
Summary: This study determined the contribution of glycosaminoglycans (GAGs) to the mechanical properties of porcine superflexor tendon (pSFT) in tension and compression. The results showed that GAGs significantly contribute to the compressive mechanical properties of pSFT, but not the tensile properties. The decellularisation process did not affect the content or function of GAGs in pSFT.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Neurosciences
Zong-Ming Li, David B. Jordan
Summary: This article reviews the movement related biomechanics, anatomical and morphological features of the carpal tunnel, and describes the pathomechanics and pathophysiology associated with carpal tunnel syndrome. It is hoped that this knowledge will improve the understanding and management of carpal tunnel syndrome.
HUMAN MOVEMENT SCIENCE
(2023)
Article
Orthopedics
Kento Hirota, Kota Watanabe, Atsushi Teramoto, Yuki Saito, Masaki Katayose
Summary: The study found a relationship between the number of FHL tendinous slips and toe flexor strength, with feet lacking FHL branching showing significantly lower strength in the third toe. Therefore, considering the number of FHL tendinous slips in an individual foot may have clinical implications for toe flexor rehabilitation or training.
FOOT AND ANKLE SURGERY
(2021)
Article
Orthopedics
Jinquan Liu, Fengming Gu, Qianyuan Liu, Wenxuan Chen, Qiuwen Ying, Yi Xu, Aiping Zhu, Li Tang, Danfeng Jing, Zhonghua Xu, Xiaoyun Pan, Jingyi Mi
Summary: This study compared the clinical efficacy of trimming and resection of the diseased superficial flexor tendon in the treatment of gouty carpal tunnel syndrome. The results showed that there was no significant difference in flexion and extension functions, pain assessment, and quality of life improvement between the two surgical methods, and excision of the superficial flexor tendon did not lead to a decrease in finger mobility. However, there may be recurrence and poor recovery after surgery.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Biophysics
Nathan D. Camarillo, Rafael Jimenez-Silva, Frances T. Sheehan
Summary: This article discusses the statistical dependence between multiple measurements from the same participant and provides recommendations for using these measurements when they are not independent.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
J. Huet, A. -S. Boureau, A. Sarcher, C. Cornu, A. Nordez
Summary: Standard compression in freehand 3D ultrasound induces a bias in volume calculations, but minimal compression and gel pad methods have similar results. With a trained examiner and precautions, the bias can be minimized and become acceptable in clinical applications.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
C. Lariviere, A. H. Eskandari, H. Mecheri, F. Ghezelbash, D. Gagnon, A. Shirazi-Adl
Summary: Recent developments in musculoskeletal modeling have focused on model customization. Personalization of the spine profile may affect estimates of spinal loading and stability. This study investigates the biomechanical consequences of changes in the spinal profile and finds that personalizing the spine profile has medium to large effects on trunk muscle forces and negligible to small effects on spinal loading and stability.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Luke T. Mattar, Arash B. Mahboobin, Adam J. Popchak, William J. Anderst, Volker Musahl, James J. Irrgang, Richard E. Debski
Summary: Exercise therapy fails in about 25.0% of cases for individuals with rotator cuff tears, and one reason for this failure may be the inability to strengthen and balance the muscle forces that keep the humeral head in the correct position. This study developed computational musculoskeletal models to compare the net muscle force before and after exercise therapy between successfully and unsuccessfully treated patients. The study found that unsuccessfully treated patients had less inferiorly oriented net muscle forces, which may increase the risk of impingement.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Natsuki Sado, Takeshi Edagawa, Toshihide Fujimori, Shogo Hashimoto, Yoshikazu Okamoto, Takahito Nakajima
Summary: The existing methods for predicting hip and lumbosacral joint centres in Japanese adults are biased and differ between sexes. We propose new regression equations that consider soft-tissue thickness, sex differences, and a height-directional measure, and validate them using leave-one-out cross-validation.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Peimin Yu, Xuanzhen Cen, Qichang Mei, Alan Wang, Yaodong Gu, Justin Fernandez
Summary: This study aimed to explore the intra-foot biomechanical differences among individuals with chronic ankle instability (CAI), copers, and healthy individuals during dynamic tasks. The study found that copers and CAI individuals had smaller dorsiflexion angles and copers presented a more eversion position compared to healthy participants. Copers also had greater dorsiflexion angles in the metatarsophalangeal joint and more inversion moments in the subtalar joint during certain tasks. These findings can help in designing interventions to restore ankle joint functions in CAI individuals.
JOURNAL OF BIOMECHANICS
(2024)
Article
Biophysics
Jon Skovgaard Jensen, Anders Holsgaard-Larsen, Anders Stengaard Sorensen, Per Aagaard, Jens Bojsen-Moller
Summary: This study investigates the biomechanical effects of robot-assisted body weight unloading (BWU) on gait patterns in healthy young adults. The results show that dynamic robot-assisted BWU enables reduced kinetic requirements without distorting biomechanically normal gait patterns during overground walking.
JOURNAL OF BIOMECHANICS
(2024)