Mallostery: Filling a niche between quality and metabolic control

“Mallostery”—ligand-dependent protein misfolding enables physiological regulation by ERAD

(2018) Margaret A Wangeline et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase

(2018) Brittany M. Johnson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

UbiA prenyltransferase domain–containing protein-1 modulates HMG-CoA reductase degradation to coordinate synthesis of sterol and nonsterol isoprenoids

(2017) Marc M. Schumacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A conserved degron containing an amphipathic helix regulates the cholesterol-mediated turnover of human squalene monooxygenase, a rate-limiting enzyme in cholesterol synthesis

(2017) Ngee Kiat Chua et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis

(2016) Anika V. Prabhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast

(2009) Renee M. Garza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY