The Molecular Chaperone HSP70 Binds to and Stabilizes NOD2, an Important Protein Involved in Crohn Disease

A Genome-Wide siRNA Screen Reveals Positive and Negative Regulators of the NOD2 and NF- B Signaling Pathways

(2013) N. Warner et al.   Science Signaling

L1CAM stimulates glioma cell motility and proliferation through the fibroblast growth factor receptor

(2012) Vishnu Mohanan et al.   CLINICAL & EXPERIMENTAL METASTASIS

The Nucleotide Synthesis Enzyme CAD Inhibits NOD2 Antibacterial Function in Human Intestinal Epithelial Cells

(2012) Amy L. Richmond et al.   GASTROENTEROLOGY

Pathogen Sensing by Nucleotide-binding Oligomerization Domain-containing Protein 2 (NOD2) Is Mediated by Direct Binding to Muramyl Dipeptide and ATP

(2012) Jinyao Mo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasomal Degradation of Nod2 Protein Mediates Tolerance to Bacterial Cell Wall Components

(2012) Kyoung-Hee Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Heat Shock Protein-70 Negatively Regulates TLR4 Signaling in the Newborn Intestinal Epithelium

(2012) A. Afrazi et al.   JOURNAL OF IMMUNOLOGY

The Innate Immune Protein Nod2 Binds Directly to MDP, a Bacterial Cell Wall Fragment

(2012) Catherine Leimkuhler Grimes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2

(2012) Milena Wiech et al.   PLoS One

RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition

(2012) S. Lipinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant human Hsp70 protects against lipoteichoic acid-induced inflammation manifestations at the cellular and organismal levels

(2011) Maxim Vinokurov et al.   CELL STRESS & CHAPERONES

Interactions Between the Host Innate Immune System and Microbes in Inflammatory Bowel Disease

(2011) Clara Abraham et al.   GASTROENTEROLOGY

Innate immune signaling in defense against intestinal microbes

(2011) Melissa A. Kinnebrew et al.   IMMUNOLOGICAL REVIEWS

Development of an All-in-One Lentiviral Vector System Based on the Original TetR for the Easy Generation of Tet-ON Cell Lines

(2011) Karim Benabdellah et al.   PLoS One

Reciprocal Control of hERG Stability by Hsp70 and Hsc70 With Implication for Restoration of LQT2 Mutant Stability

(2010) Peili Li et al.   CIRCULATION RESEARCH

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

(2010) Tilman Schneider-Poetsch et al.   Nature Chemical Biology

Bacterial clearance in Crohn's disease pathogenesis

(2010) Francesca Fava et al.   Nature Reviews Gastroenterology & Hepatology

NOD2-associated diseases: Bridging innate immunity and autoinflammation

(2009) Arturo Borzutzky et al.   CLINICAL IMMUNOLOGY

A Crohn's disease–associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1

(2009) Eiichiro Noguchi et al.   NATURE IMMUNOLOGY