The Selenium Metabolite Methylselenol Regulates the Expression of Ligands That Trigger Immune Activation through the Lymphocyte Receptor NKG2D

Effect of NKG2D ligand expression on host immune responses

(2015) Marine Champsaur et al.   IMMUNOLOGICAL REVIEWS

The NKG2D Ligand ULBP2 Is Specifically Regulated through an Invariant Chain–Dependent Endosomal Pathway

(2014) Franziska Uhlenbrock et al.   JOURNAL OF IMMUNOLOGY

Regulation of Ligands for the NKG2D Activating Receptor

(2013) David H. Raulet et al.   Annual Review of Immunology

Ancient autophagy

(2013) Daniel J. Klionsky   Autophagy

Dietary selenium supplementation modifies breast tumor growth and metastasis

(2013) Yu-Chi Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Selenium biochemistry and its role for human health

(2013) Marco Roman et al.   Metallomics

Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells

(2013) H Jiang et al.   Cell Death & Disease

Measurement of autophagy flux in the nervous system in vivo

(2013) K Castillo et al.   Cell Death & Disease

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Regulation of NKG2D-ligand cell surface expression by intracellular calcium after HDAC-inhibitor treatment

(2012) Helle Jensen et al.   MOLECULAR IMMUNOLOGY

Methylselenol Formed by Spontaneous Methylation of Selenide Is a Superior Selenium Substrate to the Thioredoxin and Glutaredoxin Systems

(2012) Aristi P. Fernandes et al.   PLoS One

Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species

(2012) Shin-Hyung Park et al.   TOXICOLOGY LETTERS

Autophagy inhibition through PI3K/Akt increases apoptosis by sodium selenite in NB4 cells

(2011) Yun Ren et al.   BMB Reports

Methylseleninic acid inhibits HDAC activity in diffuse large B-cell lymphoma cell lines

(2011) Shireen Kassam et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

An Identical miRNA of the Human JC and BK Polyoma Viruses Targets the Stress-Induced Ligand ULBP3 to Escape Immune Elimination

(2011) Yoav Bauman et al.   Cell Host & Microbe

Dietary supplementation with methylseleninic acid, but not selenomethionine, reduces spontaneous metastasis of Lewis lung carcinoma in mice

(2011) Lin Yan et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Surveying selenium speciation from soil to cell—forms and transformations

(2010) Bente Gammelgaard et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Selenium: a double-edged sword for defense and offence in cancer

(2010) Jela Brozmanová et al.   ARCHIVES OF TOXICOLOGY

The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia

(2010) H Nückel et al.   LEUKEMIA

Formation of methylselenol, dimethylselenide and dimethyldiselenide in in vitro metabolism models determined by headspace GC-MS

(2010) Charlotte Gabel-Jensen et al.   Metallomics

Investigation of the selenium metabolism in cancer cell lines

(2010) Kristoffer Lunøe et al.   Metallomics

The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination

(2010) Daphna Nachmani et al.   NATURE IMMUNOLOGY

Selenium and the Selenoprotein Thioredoxin Reductase in the Prevention, Treatment and Diagnostics of Cancer

(2009) Markus Selenius et al.   ANTIOXIDANTS & REDOX SIGNALING

 -Keto Acid Metabolites of Naturally Occurring Organoselenium Compounds as Inhibitors of Histone Deacetylase in Human Prostate Cancer Cells

(2009) J.-I. Lee et al.   Cancer Prevention Research

 -Keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells

(2009) H. Nian et al.   CARCINOGENESIS

Differential Clinical Significance of Individual NKG2D Ligands in Melanoma: Soluble ULBP2 as an Indicator of Poor Prognosis Superior to S100B

(2009) A. Paschen et al.   CLINICAL CANCER RESEARCH

Propionic Acid Secreted from Propionibacteria Induces NKG2D Ligand Expression on Human-Activated T Lymphocytes and Cancer Cells

(2009) L. Andresen et al.   JOURNAL OF IMMUNOLOGY

Methylselenol, a Selenium Metabolite, Induces Cell Cycle Arrest in G1 Phase and Apoptosis via the Extracellular-Regulated Kinase 1/2 Pathway and Other Cancer Signaling Genes

(2009) Huawei Zeng et al.   JOURNAL OF NUTRITION

High-Dose Sodium Selenite Can Induce Apoptosis of Lymphoma Cells in Adult Patients with Non-Hodgkin’s Lymphoma

(2008) Inas A. Asfour et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Novel application of 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole to visualize lysosomes in live cells

(2008) Kazuhiro Ishiguro et al.   BIOTECHNIQUES

Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia

(2008) S Talbot et al.   BRITISH JOURNAL OF PHARMACOLOGY

Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: high expression of ULBP2 is an indicator of poor prognosis

(2008) Kui Li et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Selective Induction of Expression of a Ligand for the NKG2D Receptor by Proteasome Inhibitors

(2008) M. Vales-Gomez et al.   CANCER RESEARCH

Superior in vivo inhibitory efficacy of methylseleninic acid against human prostate cancer over selenomethionine or selenite

(2008) Guang-xun Li et al.   CARCINOGENESIS

Locally Generated Methylseleninic Acid Induces Specific Inactivation of Protein Kinase C Isoenzymes

(2008) Usha Gundimeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY