Loss of Nucleolar Histone Chaperone NPM1 Triggers Rearrangement of Heterochromatin and Synergizes with a Deficiency in DNA Methyltransferase DNMT3A to Drive Ribosomal DNA Transcription

Driver mutations of cancer epigenomes

(2014) David M. Roy et al.   Protein & Cell

Chromatin states at ribosomal DNA loci

(2013) Stephan Hamperl et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Centromeres in nuclear architecture

(2013) Jan Padeken et al.   CELL CYCLE

The Nucleoplasmin Homolog NLP Mediates Centromere Clustering and Anchoring to the Nucleolus

(2013) Jan Padeken et al.   MOLECULAR CELL

The Complexity of Human Ribosome Biogenesis Revealed by Systematic Nucleolar Screening of Pre-rRNA Processing Factors

(2013) Lionel Tafforeau et al.   MOLECULAR CELL

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Linker histone H1.0 interacts with an extensive network of proteins found in the nucleolus

(2013) Anna A. Kalashnikova et al.   NUCLEIC ACIDS RESEARCH

DNA Methyltransferases in Hematologic Malignancies

(2013) Keqin Kathy Li et al.   SEMINARS IN HEMATOLOGY

Changes of the Nucleolus Architecture in Absence of the Nuclear Factor CTCF

(2012) A. Hernández-Hernández et al.   CYTOGENETIC AND GENOME RESEARCH

Formation of nuclear heterochromatin

(2012) Claudio Guetg et al.   Epigenetics

Interaction of nucleolin with ribosomal RNA genes and its role in RNA polymerase I transcription

(2012) Rong Cong et al.   NUCLEIC ACIDS RESEARCH

Heterochromatin Formation Promotes Longevity and Represses Ribosomal RNA Synthesis

(2012) Kimberly Larson et al.   PLoS Genetics

The Multifunctional Protein Nucleophosmin (NPM1) Is a Human Linker Histone H1 Chaperone

(2011) Shrikanth S. Gadad et al.   BIOCHEMISTRY

HP1  links histone methylation marks to meiotic synapsis in mice

(2011) Y. Takada et al.   DEVELOPMENT

A role for heterochromatin protein 1  at human telomeres

(2011) S. Canudas et al.   GENES & DEVELOPMENT

Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases

(2011) E Colombo et al.   ONCOGENE

The CCCTC-Binding Factor (CTCF) of Drosophila Contributes to the Regulation of the Ribosomal DNA and Nucleolar Stability

(2011) Paola A. Guerrero et al.   PLoS One

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression

(2011) Q. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome organization in and around the nucleolus

(2011) Attila Németh et al.   TRENDS IN GENETICS

An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction

(2010) Everardo Macias et al.   CANCER CELL

Specific activation of the p53 pathway by low dose actinomycin D: A new route to p53 based cyclotherapy

(2010) Meng Ling Choong et al.   CELL CYCLE

Chemotherapeutic Drugs Inhibit Ribosome Biogenesis at Various Levels

(2010) Kaspar Burger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits

(2010) Marie-Françoise O’Donohue et al.   JOURNAL OF CELL BIOLOGY

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

B23 acts as a nucleolar stress sensor and promotes cell survival through its dynamic interaction with hnRNPU and hnRNPA1

(2010) Z Yao et al.   ONCOGENE

Silencing of Ribosomal Protein S9 Elicits a Multitude of Cellular Responses Inhibiting the Growth of Cancer Cells Subsequent to p53 Activation

(2010) Mikael S. Lindström et al.   PLoS One

Characterization of the DOT1L Network: Implications of Diverse Roles for DOT1L

(2010) Geunyeong Park et al.   PROTEIN JOURNAL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

SUV39h-independent association of HP1β with fibrillarin-positive nucleolar regions

(2009) Andrea Harničarová Horáková et al.   CHROMOSOMA

Linker histone H1 is essential for Drosophila development, the establishment of pericentric heterochromatin, and a normal polytene chromosome structure

(2009) X. Lu et al.   GENES & DEVELOPMENT

CTCF and its protein partners: divide and rule?

(2009) J. Zlatanova et al.   JOURNAL OF CELL SCIENCE

Structure and Epigenetics of Nucleoli in Comparison With Non-nucleolar Compartments

(2009) Eva Bártová et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Loss of Human Ribosomal Gene CpG Methylation Enhances Cryptic RNA Polymerase II Transcription and Disrupts Ribosomal RNA Processing

(2009) Thérèse Gagnon-Kugler et al.   MOLECULAR CELL

The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology

(2008) Brian McStay et al.   Annual Review of Cell and Developmental Biology

SIRT1 regulates the ribosomal DNA locus: Epigenetic candles twinkle longevity in the Christmas tree

(2008) Antero Salminen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Depletion of nucleophosmin leads to distortion of nucleolar and nuclear structures in HeLa cells

(2008) Mohammed Abdullahel Amin et al.   BIOCHEMICAL JOURNAL

Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse

(2008) P. Sportoletti et al.   BLOOD

Chromatin: linking structure and function in the nucleolus

(2008) Peter C. McKeown et al.   CHROMOSOMA

Ribosomal Protein S9 Is a Novel B23/NPM-binding Protein Required for Normal Cell Proliferation

(2008) Mikael S. Lindström et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7γ

(2008) Paola Bonetti et al.   JOURNAL OF CELL BIOLOGY

Transcription Regulation of the rRNA Gene by a Multifunctional Nucleolar Protein, B23/Nucleophosmin, through Its Histone Chaperone Activity

(2008) K. Murano et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome

(2008) L. B. Maggi et al.   MOLECULAR AND CELLULAR BIOLOGY