The Cdc20-binding Phe Box of the Spindle Checkpoint Protein BubR1 Maintains the Mitotic Checkpoint Complex During Mitosis

Genome‐wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

(2014) Laura A Díaz‐Martínez et al.   EMBO JOURNAL

Thyroid Hormone Receptor Interacting Protein 13 (TRIP13) AAA-ATPase Is a Novel Mitotic Checkpoint-silencing Protein

(2014) Kexi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple mechanisms determine the order of APC/C substrate degradation in mitosis

(2014) Dan Lu et al.   JOURNAL OF CELL BIOLOGY

The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C

(2014) Daisuke Izawa et al.   NATURE

Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31comet

(2014) E. Eytan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

(2014) Joo Seok Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 Complex

(2013) Jun He et al.   MOLECULAR CELL

Kinetic framework of spindle assembly checkpoint signalling

(2013) Amalie E. Dick et al.   NATURE CELL BIOLOGY

The spindle assembly checkpoint works like a rheostat rather than a toggle switch

(2013) Philippe Collin et al.   NATURE CELL BIOLOGY

Determinants of robustness in spindle assembly checkpoint signalling

(2013) Stephanie Heinrich et al.   NATURE CELL BIOLOGY

Tracking spindle checkpoint signals from kinetochores to APC/C

(2013) Luying Jia et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitosis: Short-Circuiting Spindle Checkpoint Signaling

(2012) Xuelian Luo et al.   CURRENT BIOLOGY

The Spindle Assembly Checkpoint

(2012) Pablo Lara-Gonzalez et al.   CURRENT BIOLOGY

Integration of Kinase and Phosphatase Activities by BUBR1 Ensures Formation of Stable Kinetochore-Microtubule Attachments

(2012) Saskia J.E. Suijkerbuijk et al.   DEVELOPMENTAL CELL

Losing balance: the origin and impact of aneuploidy in cancer

(2012) Andrew J Holland et al.   EMBO REPORTS

The APC/C Subunit Mnd2/Apc15 Promotes Cdc20 Autoubiquitination and Spindle Assembly Checkpoint Inactivation

(2012) Scott A. Foster et al.   MOLECULAR CELL

Structure of the mitotic checkpoint complex

(2012) William C. H. Chao et al.   NATURE

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

(2012) Emily A. Foley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural analysis of human Cdc20 supports multisite degron recognition by APC/C

(2012) W. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of pseudosubstrate inhibition of the anaphase promoting complex by Acm1

(2011) Janet L Burton et al.   EMBO JOURNAL

BUBR1 and Closed MAD2 (C-MAD2) Interact Directly to Assemble a Functional Mitotic Checkpoint Complex

(2011) Aaron R. Tipton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit

(2011) F. G. Westhorpe et al.   JOURNAL OF CELL SCIENCE

BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner

(2011) Pablo Lara-Gonzalez et al.   JOURNAL OF CELL SCIENCE

Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31comet

(2011) Luying Jia et al.   MOLECULAR BIOLOGY OF THE CELL

Homeostatic Control of Mitotic Arrest

(2011) Gianluca Varetti et al.   MOLECULAR CELL

How APC/C–Cdc20 changes its substrate specificity in mitosis

(2011) Daisuke Izawa et al.   NATURE CELL BIOLOGY

p31comet promotes disassembly of the mitotic checkpoint complex in an ATP-dependent process

(2011) A. Teichner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutual regulation between the spindle checkpoint and APC/C

(2011) Soonjoung Kim et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Kinetochore–microtubule interactions: steps towards bi-orientation

(2010) Tomoyuki U Tanaka   EMBO JOURNAL

Structures of APC/CCdh1 with substrates identify Cdh1 and Apc10 as the D-box co-receptor

(2010) Paula C. A. da Fonseca et al.   NATURE

Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1

(2010) Bettina A Buschhorn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

BubR1 N Terminus Acts as a Soluble Inhibitor of Cyclin B Degradation by APC/CCdc20 in Interphase

(2009) Liviu A. Malureanu et al.   DEVELOPMENTAL CELL

BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis

(2009) Eunhee Choi et al.   EMBO JOURNAL

Structure of the Anaphase-Promoting Complex/Cyclosome Interacting with a Mitotic Checkpoint Complex

(2009) F. Herzog et al.   SCIENCE

The Spindle Checkpoint Functions of Mad3 and Mad2 Depend on a Mad3 KEN Box-mediated Interaction with Cdc20-Anaphase-promoting Complex (APC/C)

(2008) Matylda Sczaniecka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1

(2008) Jungseog Kang et al.   MOLECULAR CELL

Protein Metamorphosis: The Two-State Behavior of Mad2

(2008) Xuelian Luo et al.   STRUCTURE

Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer

(2008) Maojun Yang et al.   PLOS BIOLOGY

Molecular architecture of the kinetochore–microtubule interface

(2007) Iain M. Cheeseman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY