Expression of the ORMDLS, Modulators of Serine Palmitoyltransferase, Is Regulated by Sphingolipids in Mammalian Cells
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Title
Expression of the ORMDLS, Modulators of Serine Palmitoyltransferase, Is Regulated by Sphingolipids in Mammalian Cells
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 1, Pages 90-98
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-11-14
DOI
10.1074/jbc.m114.588236
References
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Related references
Note: Only part of the references are listed.- Signal transducer and activator of transcription 6 directly regulates human ORMDL3 expression
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- Phosphorylation of Serine Palmitoyltransferase Long Chain-1 (SPTLC1) on Tyrosine 164 Inhibits Its Activity and Promotes Cell Survival
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- Topological and Functional Characterization of the ssSPTs, Small Activating Subunits of Serine Palmitoyltransferase
- (2013) Jeffrey M. Harmon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Orm Proteins Integrate Multiple Signals to Maintain Sphingolipid Homeostasis
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- TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis
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- Promoter Characterization and Role of cAMP/PKA/CREB in the Basal Transcription of the Mouse ORMDL3 Gene
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- Impaired Sphingolipid Synthesis in the Respiratory Tract Induces Airway Hyperreactivity
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- Mechanisms elevating ORMDL3 expression in recurrent wheeze patients: Role of Ets-1, p300 and CREB
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- Mammalian ORMDL Proteins Mediate the Feedback Response in Ceramide Biosynthesis
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- Regulation of sphingolipid synthesis through Orm1 and Orm2 in yeast
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- Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways
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- ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6
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- Hereditary Sensory Neuropathy Type 1 Is Caused by the Accumulation of Two Neurotoxic Sphingolipids
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- Orm family proteins mediate sphingolipid homeostasis
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- Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control
- (2010) S. Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress
- (2009) Gerard Cantero-Recasens et al. HUMAN MOLECULAR GENETICS
- Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities
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- ORMDL3Gene Is Associated with Asthma in Three Ethnically Diverse Populations
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- Ceramide Synthase Inhibition by Fumonisin B1Causes Accumulation of 1-Deoxysphinganine
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