HIV-1 Protein Nef Inhibits Activity of ATP-binding Cassette Transporter A1 by Targeting Endoplasmic Reticulum Chaperone Calnexin

The ABCA1 domain responsible for interaction with HIV-1 Nef is conformational and not linear

(2014) Daria Jacob et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Infection duration and inflammatory imbalance are associated with atherosclerotic risk in HIV-infected never-smokers independent of antiretroviral therapy

(2013) Moïse Desvarieux et al.   AIDS

ABCA12 Regulates ABCA1-Dependent Cholesterol Efflux from Macrophages and the Development of Atherosclerosis

(2013) Ying Fu et al.   Cell Metabolism

Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection

(2012) Larisa Dubrovsky et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux

(2012) Huanhuan L. Cui et al.   JOURNAL OF LIPID RESEARCH

Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux

(2012) Hong Jiang et al.   Lipids in Health and Disease

Cardiovascular implications of HIV-induced dyslipidemia

(2011) Chiara Giannarelli et al.   ATHEROSCLEROSIS

HIV-1 Nef Disrupts Intracellular Trafficking of Major Histocompatibility Complex Class I, CD4, CD8, and CD28 by Distinct Pathways That Share Common Elements

(2011) J. A. Leonard et al.   JOURNAL OF VIROLOGY

HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms

(2011) Mohamad Navab et al.   Nature Reviews Cardiology

Mutation of the ATP Cassette Binding Transporter A1 (ABCA1) C-Terminus Disrupts HIV-1 Nef Binding but Does Not Block the Nef Enhancement of ABCA1 Protein Degradation

(2010) Zahedi Mujawar et al.   BIOCHEMISTRY

Mapping of Domains on HIV Envelope Protein Mediating Association with Calnexin and Protein-disulfide Isomerase

(2010) Marie-Jeanne Papandréou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating Nef Induces Dyslipidemia in Simian Immunodeficiency Virus–Infected Macaques by Suppressing Cholesterol Efflux

(2010) Bela F. Asztalos et al.   JOURNAL OF INFECTIOUS DISEASES

Stimulation of the Liver X Receptor Pathway Inhibits HIV-1 Replication via Induction of ATP-Binding Cassette Transporter A1

(2010) M. P. Morrow et al.   MOLECULAR PHARMACOLOGY

The ABCA1 Q597R mutant undergoes trafficking from the ER upon ER stress

(2008) Arowu R. Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SPTLC1 Binds ABCA1 To Negatively Regulate Trafficking and Cholesterol Efflux Activity of the Transporter†

(2008) Norimasa Tamehiro et al.   BIOCHEMISTRY

Getting In and Out from Calnexin/Calreticulin Cycles

(2008) Julio J. Caramelo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY