HIV-1 Nef Disrupts Intracellular Trafficking of Major Histocompatibility Complex Class I, CD4, CD8, and CD28 by Distinct Pathways That Share Common Elements

A Novel Trafficking Signal within the HLA-C Cytoplasmic Tail Allows Regulated Expression upon Differentiation of Macrophages

(2014) M. R. Schaefer et al.   JOURNAL OF IMMUNOLOGY

HIV-1 Nef Binds a Subpopulation of MHC-I throughout Its Trafficking Itinerary and Down-regulates MHC-I by Perturbing Both Anterograde and Retrograde Trafficking

(2010) Ling Yi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1-infected CD8+CD4+ T cells decay in vivo at a similar rate to infected CD4 T cells during HAART

(2009) Gareth J Hughes et al.   AIDS

Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface

(2009) A. Zloza et al.   BLOOD

Massive Secretion by T Cells Is Caused by HIV Nef in Infected Cells and by Nef Transfer to Bystander Cells

(2009) Claudia Muratori et al.   Cell Host & Microbe

Phenotypic and Functional Characterization of HIV-1-Specific CD4+CD8+ Double-Positive T Cells in Early and Chronic HIV-1 Infection

(2009) Rawleigh Howe et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

A Basic Patch on  -Adaptin Is Required for Binding of Human Immunodeficiency Virus Type 1 Nef and Cooperative Assembly of a CD4-Nef-AP-2 Complex

(2009) R. Chaudhuri et al.   JOURNAL OF VIROLOGY

An MHC-I Cytoplasmic Domain/HIV-1 Nef Fusion Protein Binds Directly to the μ Subunit of the AP-1 Endosomal Coat Complex

(2009) Rajendra Kumar Singh et al.   PLoS One

Proportion of HIV-1 Infected CD8+CD4- T Lymphocytes In Vivo

(2008) Naveed Gulzar et al.   CURRENT HIV RESEARCH

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

(2008) Bernard T. Kelly et al.   NATURE

HIV-1 Nef Induces a Rab11-Dependent Routing of Endocytosed Immune Costimulatory Proteins CD80 and CD86 to the Golgi

(2008) Ashutosh Chaudhry et al.   TRAFFIC

HIV-1 Nef Targets MHC-I and CD4 for Degradation Via a Final Common β-COP–Dependent Pathway in T Cells

(2008) Malinda R. Schaefer et al.   PLoS Pathogens