Distinct Effects of themesenchymal dysplasiaGene Variant of Murine Patched-1 Protein on Canonical and Non-canonical Hedgehog Signaling Pathways

Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1

(2012) Hong Chang et al.   DEVELOPMENTAL BIOLOGY

Reduced white fat mass in adult mice bearing a truncated Patched 1

(2012) Zili Li et al.   International Journal of Biological Sciences

Hedgehog pathway as a drug target: Smoothened inhibitors in development

(2012) Tara Lin et al.   OncoTargets and Therapy

Hedgehog Fights Back: Mechanisms of Acquired Resistance against Smoothened Antagonists

(2011) C. Metcalfe et al.   CANCER RESEARCH

Boc and Gas1 Each Form Distinct Shh Receptor Complexes with Ptch1 and Are Required for Shh-Mediated Cell Proliferation

(2011) Luisa Izzi et al.   DEVELOPMENTAL CELL

Overlapping Roles and Collective Requirement for the Coreceptors GAS1, CDO, and BOC in SHH Pathway Function

(2011) Benjamin L. Allen et al.   DEVELOPMENTAL CELL

Sonic Hedgehog Activates the GTPases Rac1 and RhoA in a Gli-Independent Manner Through Coupling of Smoothened to Gi Proteins

(2011) A. H. Polizio et al.   Science Signaling

Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

(2010) Pilar Chinchilla et al.   CELL CYCLE

Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling

(2010) Hong Chang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

All Mammalian Hedgehog Proteins Interact with Cell Adhesion Molecule, Down-regulated by Oncogenes (CDO) and Brother of CDO (BOC) in a Conserved Manner

(2010) Jennifer M. Kavran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation

(2009) R. C. Moraes et al.   DEVELOPMENT

c-Src Associates with ErbB2 through an Interaction between Catalytic Domains and Confers Enhanced Transforming Potential

(2009) R. Marcotte et al.   MOLECULAR AND CELLULAR BIOLOGY

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

The Role of Src in Solid Tumors

(2009) D. L. Wheeler et al.   ONCOLOGIST

Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo)

(2008) Xiaomei Zhang et al.   BREAST CANCER RESEARCH AND TREATMENT