All Mammalian Hedgehog Proteins Interact with Cell Adhesion Molecule, Down-regulated by Oncogenes (CDO) and Brother of CDO (BOC) in a Conserved Manner

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Genetic and biochemical definition of the Hedgehog receptor

(2010) X. Zheng et al.   GENES & DEVELOPMENT

Brachydactyly A-1 mutations restricted to the central region of the N-terminal active fragment of Indian Hedgehog

(2009) Ashley M Byrnes et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP

(2009) Benjamin Bishop et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling

(2009) Ivan Bosanac et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

(2009) Charles M. Rudin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

(2009) Suzie J. Scales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Nanoscale Organization of Hedgehog Is Essential for Long-Range Signaling

(2008) Neha Vyas et al.   CELL

The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla

(2008) Jason S. McLellan et al.   NATURE