Loss of TBL1XR1 Disrupts Glucocorticoid Receptor Recruitment to Chromatin and Results in Glucocorticoid Resistance in a B-Lymphoblastic Leukemia Model

Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011

(2013) L Olsson et al.   LEUKEMIA

The expression of histone deacetylase 4 is associated with prednisone poor-response in childhood acute lymphoblastic leukemia

(2013) Bernd Gruhn et al.   LEUKEMIA RESEARCH

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia

(2012) T. Bhatla et al.   BLOOD

Recurrent Mutations of MYD88 and TBL1XR1 in Primary Central Nervous System Lymphomas

(2012) A. Gonzalez-Aguilar et al.   CLINICAL CANCER RESEARCH

B-lineage transcription factors and cooperating gene lesions required for leukemia development

(2012) E Tijchon et al.   LEUKEMIA

The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution

(2012) Esmé Waanders et al.   PLoS Genetics

Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies

(2011) L. E. Hogan et al.   BLOOD

Glucocorticoid receptor-mediated apoptosis: mechanisms of resistance in cancer cells

(2011) George Schlossmacher et al.   JOURNAL OF ENDOCRINOLOGY

Clinical and Laboratory Biology of Childhood Acute Lymphoblastic Leukemia

(2011) William L. Carroll et al.   JOURNAL OF PEDIATRICS

Reversible SUMOylation of TBL1-TBLR1 Regulates β-Catenin-Mediated Wnt Signaling

(2011) Hyo-Kyoung Choi et al.   MOLECULAR CELL

CREBBP mutations in relapsed acute lymphoblastic leukaemia

(2011) Charles G. Mullighan et al.   NATURE

Analysis of the coding genome of diffuse large B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE GENETICS

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

(2010) J. C. van Galen et al.   BLOOD

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition

(2010) P. S. Bachmann et al.   BLOOD

research paper: Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia

(2010) Daniel Antunes Moreno et al.   BRITISH JOURNAL OF HAEMATOLOGY

Pro-apoptotic protein BIM in apoptosis of glucocorticoid-sensitive and -resistant acute lymphoblastic leukemia CEM cells

(2010) Ya-ning Zhao et al.   MEDICAL ONCOLOGY

Kinetic Complexity of the Global Response to Glucocorticoid Receptor Action

(2009) Sam John et al.   ENDOCRINOLOGY

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

(2009) S. Ghisletti et al.   GENES & DEVELOPMENT

Receptor mutation is not a common mechanism of naturally occurring glucocorticoid resistance in leukaemia cell lines

(2008) Alex H. Beesley et al.   LEUKEMIA RESEARCH

TBL1 and TBLR1 Phosphorylation on Regulated Gene Promoters Overcomes Dual CtBP and NCoR/SMRT Transcriptional Repression Checkpoints

(2008) Valentina Perissi et al.   MOLECULAR CELL

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

(2008) C. G. Mullighan et al.   SCIENCE