The Second Sodium Site in the Dopamine Transporter Controls Cation Permeation and Is Regulated by Chloride

Missense dopamine transporter mutations associate with adult parkinsonism and ADHD

(2014) Freja H. Hansen et al.   JOURNAL OF CLINICAL INVESTIGATION

The Two Na+Sites in the Human Serotonin Transporter Play Distinct Roles in the Ion Coupling and Electrogenicity of Transport

(2013) Bruce Felts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder

(2013) P J Hamilton et al.   MOLECULAR PSYCHIATRY

X-ray structure of dopamine transporter elucidates antidepressant mechanism

(2013) Aravind Penmatsa et al.   NATURE

Chloride binding site of neurotransmitter sodium symporters

(2013) A. K. Kantcheva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using lithium to probe sequential cation interactions with GAT1

(2012) Anne-Kristine Meinild et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

The Role of Local Hydration and Hydrogen-Bonding Dynamics in Ion and Solute Release from Ion-Coupled Secondary Transporters

(2011) Chunfeng Zhao et al.   BIOCHEMISTRY

Unifying Concept of Serotonin Transporter-associated Currents

(2011) Klaus Schicker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Conserved Asparagine Residue in Transmembrane Segment 1 (TM1) of Serotonin Transporter Dictates Chloride-coupled Neurotransmitter Transport

(2011) L. Keith Henry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The monoamine neurotransmitter disorders: an expanding range of neurological syndromes

(2011) Manju A Kurian et al.   LANCET NEUROLOGY

How Addictive Drugs Disrupt Presynaptic Dopamine Neurotransmission

(2011) David Sulzer   NEURON

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

Substrate-dependent proton antiport in neurotransmitter:sodium symporters

(2010) Yongfang Zhao et al.   Nature Chemical Biology

Molecular Mechanism of Ion-Ion and Ion-Substrate Coupling in the Na+-Dependent Leucine Transporter LeuT

(2008) David A. Caplan et al.   BIOPHYSICAL JOURNAL

Control of Ion Selectivity in LeuT: Two Na+ Binding Sites with Two Different Mechanisms

(2008) Sergei Y. Noskov et al.   JOURNAL OF MOLECULAR BIOLOGY

Currents in Response to Rapid Concentration Jumps of Amphetamine Uncover Novel Aspects of Human Dopamine Transporter Function

(2008) K. Erreger et al.   JOURNAL OF NEUROSCIENCE

Anomalous Dopamine Release Associated with a Human Dopamine Transporter Coding Variant

(2008) M. S. Mazei-Robison et al.   JOURNAL OF NEUROSCIENCE

The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site

(2008) Lei Shi et al.   MOLECULAR CELL

The binding sites for cocaine and dopamine in the dopamine transporter overlap

(2008) Thijs Beuming et al.   NATURE NEUROSCIENCE

A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation

(2008) S. K. Singh et al.   SCIENCE