Nuclear Heme Oxygenase-1 (HO-1) Modulates Subcellular Distribution and Activation of Nrf2, Impacting Metabolic and Anti-oxidant Defenses

Signaling Function of Heme Oxygenase Proteins

(2013) Phyllis A. Dennery   ANTIOXIDANTS & REDOX SIGNALING

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway

(2013) Ulkan Kilic et al.   Nutrition & Metabolism

Mechanisms of Nrf2/Keap1-Dependent Phase II Cytoprotective and Detoxifying Gene Expression and Potential Cellular Targets of Chemopreventive Isothiocyanates

(2013) Biswa Nath Das et al.   Oxidative Medicine and Cellular Longevity

Glucose availability is a decisive factor for Nrf2-mediated gene expression

(2013) Elke H. Heiss et al.   Redox Biology

Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: Role of β-catenin/hnRNPK signaling

(2013) Guang Yang et al.   Redox Biology

The Predicted Molecular Weight of Nrf2: It Is What It Is Not

(2012) Alexandria Lau et al.   ANTIOXIDANTS & REDOX SIGNALING

Biomarkers of Response to Akt Inhibitor MK-2206 in Breast Cancer

(2012) T. Sangai et al.   CLINICAL CANCER RESEARCH

The transcription factor NF-E2-related Factor 2 (Nrf2): a protooncogene?

(2012) Phillip Shelton et al.   FASEB JOURNAL

Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/ -TrCP Axis

(2012) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

(2012) S Chowdhry et al.   ONCOGENE

4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling

(2011) Huang-Hui Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acetylation-Deacetylation of the Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-related Factor 2) Regulates Its Transcriptional Activity and Nucleocytoplasmic Localization

(2011) Yumiko Kawai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

(2011) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of the Nrf2–Keap1 Antioxidant Response by the Ubiquitin Proteasome System: An Insight into Cullin-Ring Ubiquitin Ligases

(2010) Nicole F. Villeneuve et al.   ANTIOXIDANTS & REDOX SIGNALING

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NRF2 Cysteine Residues Are Critical for Oxidant/Electrophile-Sensing, Kelch-Like ECH-Associated Protein-1-Dependent Ubiquitination-Proteasomal Degradation, and Transcription Activation

(2009) X. He et al.   MOLECULAR PHARMACOLOGY

Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin

(2009) Francesc X. Soriano et al.   MOLECULES AND CELLS

Manipulation of Gene Expression by Oxygen: A Primer From Bedside to Bench

(2009) Clyde J Wright et al.   PEDIATRIC RESEARCH

Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response

(2009) Zheng Sun et al.   PLoS One

Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress

(2007) Qing S. Lin et al.   FREE RADICAL BIOLOGY AND MEDICINE