Mitochondrial Complex I Deficiency Enhances Skeletal Myogenesis but Impairs Insulin Signaling through SIRT1 Inactivation

"Deficiency" of Mitochondria in Muscle Does Not Cause Insulin Resistance

(2013) J. O. Holloszy   DIABETES

Muscle regeneration in mitochondrial myopathies

(2013) T.O. Krag et al.   MITOCHONDRION

mTOR Inhibition Alleviates Mitochondrial Disease in a Mouse Model of Leigh Syndrome

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Mitochondria as a Potential Regulator of Myogenesis

(2013) Akira Wagatsuma et al.   TheScientificWorldJOURNAL

MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling

(2013) Jae-Sung Yi et al.   Nature Communications

Adipose-Specific Deletion of TFAM Increases Mitochondrial Oxidation and Protects Mice against Obesity and Insulin Resistance

(2012) Cecile Vernochet et al.   Cell Metabolism

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

OXPHOS mutations and neurodegeneration

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Mitochondrial diseases

(2012) Anthony HV Schapira   LANCET

Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells

(2012) Marco Spinazzi et al.   Nature Protocols

Sirtuins mediate mammalian metabolic responses to nutrient availability

(2012) Angeliki Chalkiadaki et al.   Nature Reviews Endocrinology

Respiratory chain complex I deficiency caused by mitochondrial DNA mutations

(2011) Helen Swalwell et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Sirtuin 1 (SIRT1) Deacetylase Activity Is Not Required for Mitochondrial Biogenesis or Peroxisome Proliferator-activated Receptor-γ Coactivator-1α (PGC-1α) Deacetylation following Endurance Exercise

(2011) Andrew Philp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of SirT1 in muscle mitochondrial turnover

(2011) Keir J. Menzies et al.   MITOCHONDRION

TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2

(2010) Soon-Young Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1

(2010) C S Lee et al.   CELL DEATH AND DIFFERENTIATION

Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity

(2010) Christoph Zechner et al.   Cell Metabolism

Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

(2010) N. Lefort et al.   DIABETES

High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency

(2010) Sarah E Calvo et al.   NATURE GENETICS

Mitochondrial oxidative phosphorylation system is recruited to detergent-resistant lipid rafts during myogenesis

(2010) Bong-Woo Kim et al.   PROTEOMICS

Proteomics Analysis of Human Skeletal Muscle Reveals Novel Abnormalities in Obesity and Type 2 Diabetes

(2009) H. Hwang et al.   DIABETES

SIRT1 Controls the Transcription of the Peroxisome Proliferator-activated Receptor-γ Co-activator-1α (PGC-1α) Gene in Skeletal Muscle through the PGC-1α Autoregulatory Loop and Interaction with MyoD

(2009) Ramon Amat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of mitochondrial biogenesis during myogenesis

(2009) A.H.V. Remels et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy

(2008) Shane E. Kruse et al.   Cell Metabolism

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

(2008) Marcella Fulco et al.   DEVELOPMENTAL CELL

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

Asian Indians Have Enhanced Skeletal Muscle Mitochondrial Capacity to Produce ATP in Association With Severe Insulin Resistance

(2008) K. S. Nair et al.   DIABETES

Secretion of adenylate kinase 1 is required for extracellular ATP synthesis in C2C12 myotubes

(2008) Hyo-Jung Choo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Role of mitochondria and reactive oxygen species in dendritic cell differentiation and functions

(2008) Annalisa Del Prete et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Disease in Autism Spectrum Disorder Patients: A Cohort Analysis

(2008) Jacqueline R. Weissman et al.   PLoS One