Overlapping and Opposing Functions of G Protein-coupled Receptor Kinase 2 (GRK2) and GRK5 during Heart Development

G Protein–Coupled Receptor Kinase 2

(2014) Meryl C. Woodall et al.   CIRCULATION RESEARCH

Prodeath Signaling of G Protein–Coupled Receptor Kinase 2 in Cardiac Myocytes After Ischemic Stress Occurs Via Extracellular Signal–Regulated Kinase-Dependent Heat Shock Protein 90–Mediated Mitochondrial Targeting

(2013) Mai Chen et al.   CIRCULATION RESEARCH

Toxicity and enantiospecific differences of two β-blockers, propranolol and metoprolol, in the embryos and larvae of zebrafish (Danio rerio)

(2013) Liwei Sun et al.   ENVIRONMENTAL TOXICOLOGY

Regulation of Nuclear Factor κB (NF-κB) in the Nucleus of Cardiomyocytes by G Protein-coupled Receptor Kinase 5 (GRK5)

(2013) Kazi N. Islam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developmental and tumoral vascularization is regulated by G protein–coupled receptor kinase 2

(2013) Verónica Rivas et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac Progenitor Cells Engineered With βARKct Have Enhanced β-Adrenergic Tolerance

(2013) Mohsin Khan et al.   MOLECULAR THERAPY

Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process

(2013) Jessica I. Gold et al.   PLoS One

Grk5l Controls Heart Development by Limiting mTOR Signaling during Symmetry Breaking

(2013) Martin D. Burkhalter et al.   Cell Reports

Effects of propranolol on heart rate and development in Japanese medaka (Oryzias latipes) and zebrafish (Danio rerio)

(2012) Juliane Finn et al.   AQUATIC TOXICOLOGY

Determining the Absolute Requirement of G Protein–Coupled Receptor Kinase 5 for Pathological Cardiac Hypertrophy

(2012) Jessica I. Gold et al.   CIRCULATION RESEARCH

G Protein-coupled Receptor Kinase 5 Is Localized to Centrosomes and Regulates Cell Cycle Progression

(2012) Allison M. Michal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling

(2012) Domitille Heitzler et al.   Molecular Systems Biology

The Origin and Evolution of G Protein-Coupled Receptor Kinases

(2012) Arcady Mushegian et al.   PLoS One

Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis

(2011) Anna Fusco et al.   CELLULAR SIGNALLING

G protein-coupled receptor kinases in normal and failing myocardium

(2011) Zheng Maggie Huang   Frontiers in Bioscience-Landmark

Growth Arrest Specific 8 (Gas8) and G Protein-coupled Receptor Kinase 2 (GRK2) Cooperate in the Control of Smoothened Signaling

(2011) Tama Evron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo and in vitro assessment of cardiac  -adrenergic receptors in larval zebrafish (Danio rerio)

(2011) S. L. Steele et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

PINCH Proteins Regulate Cardiac Contractility by Modulating Integrin-Linked Kinase-Protein Kinase B Signaling

(2011) B. Meder et al.   MOLECULAR AND CELLULAR BIOLOGY

Quantitative Encoding of the Effect of a Partial Agonist on Individual Opioid Receptors by Multisite Phosphorylation and Threshold Detection

(2011) E. K. Lau et al.   Science Signaling

Distinct Phosphorylation Sites on the  2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of  -Arrestin

(2011) K. N. Nobles et al.   Science Signaling

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

(2010) Y. Wang et al.   DEVELOPMENT

Intracardiac Injection of AdGRK5-NT Reduces Left Ventricular Hypertrophy by Inhibiting NF-κB–Dependent Hypertrophic Gene Expression

(2010) Daniela Sorriento et al.   HYPERTENSION

Role of the Amino Terminus of G Protein-Coupled Receptor Kinase 2 in Receptor Phosphorylation

(2009) Christina S. Pao et al.   BIOCHEMISTRY

G Protein-coupled Receptor Kinases Phosphorylate LRP6 in the Wnt Pathway

(2009) Minyong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential

(2008) N. A. Thomas et al.   DEVELOPMENT

Smoothened Signaling in Vertebrates Is Facilitated by a G Protein-coupled Receptor Kinase

(2008) Melanie Philipp et al.   MOLECULAR BIOLOGY OF THE CELL

A GRK5 polymorphism that inhibits β-adrenergic receptor signaling is protective in heart failure

(2008) Stephen B Liggett et al.   NATURE MEDICINE

Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

(2008) J. S. Martini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols