Mechanism and Function of Monoclonal Antibodies Targeting Siglec-15 for Therapeutic Inhibition of Osteoclastic Bone Resorption

Siglec-15 Regulates Osteoclast Differentiation by Modulating RANKL-Induced Phosphatidylinositol 3-Kinase/Akt and Erk Pathways in Association With Signaling Adaptor DAP12

(2013) Yusuke Kameda et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Impaired osteoclast differentiation and function and mild osteopetrosis development in Siglec-15-deficient mice

(2012) Yoshiharu Hiruma et al.   BONE

Bone histomorphometry using free and commonly available software

(2012) Kevin P Egan et al.   HISTOPATHOLOGY

Siglec-15 Protein Regulates Formation of Functional Osteoclasts in Concert with DNAX-activating Protein of 12 kDa (DAP12)

(2012) Norihiro Ishida-Kitagawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Siglec-15, a member of the sialic acid-binding lectin, is a novel regulator for osteoclast differentiation

(2011) Yoshiharu Hiruma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bisphosphonate Use and the Risk of Subtrochanteric or Femoral Shaft Fractures in Older Women

(2011) Laura Y. Park-Wyllie   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Denosumab and bisphosphonates: Different mechanisms of action and effects

(2010) Roland Baron et al.   BONE

Cellular and Molecular Mechanisms of Bone Remodeling

(2010) Liza J. Raggatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BM 21.0955, a potent new bisphosphonate to inhibit bone resorption

(2010) R.C. Mühlbauer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Siglecs as targets for therapy in immune-cell-mediated disease

(2009) Mary K. O’Reilly et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Siglecs as positive and negative regulators of the immune system: Figure 1

(2008) Paul R. Crocker et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

DAP10- and DAP12-associated receptors in innate immunity

(2008) Lewis L. Lanier   IMMUNOLOGICAL REVIEWS

CD22: an inhibitory enigma

(2008) Jennifer A. Walker et al.   IMMUNOLOGY

NFATc1 Induces Osteoclast Fusion Via Up-Regulation of Atp6v0d2 and the Dendritic Cell-Specific Transmembrane Protein (DC-STAMP)

(2007) Kabsun Kim et al.   MOLECULAR ENDOCRINOLOGY