Siglec-15 Regulates Osteoclast Differentiation by Modulating RANKL-Induced Phosphatidylinositol 3-Kinase/Akt and Erk Pathways in Association With Signaling Adaptor DAP12

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

Impaired osteoclast differentiation and function and mild osteopetrosis development in Siglec-15-deficient mice

(2012) Yoshiharu Hiruma et al.   BONE

Siglec-15 Protein Regulates Formation of Functional Osteoclasts in Concert with DNAX-activating Protein of 12 kDa (DAP12)

(2012) Norihiro Ishida-Kitagawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: Role of the Akt pathway and the ERK/Bim axis

(2011) Takumi Matsumoto et al.   ARTHRITIS AND RHEUMATISM

Siglec-15, a member of the sialic acid-binding lectin, is a novel regulator for osteoclast differentiation

(2011) Yoshiharu Hiruma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice

(2011) Alexander David Barrow et al.   JOURNAL OF CLINICAL INVESTIGATION

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cytoskeletal dysfunction dominates in DAP12-deficient osteoclasts

(2010) W. Zou et al.   JOURNAL OF CELL SCIENCE

SLP-76 Couples Syk to the Osteoclast Cytoskeleton

(2009) J. L. Reeve et al.   JOURNAL OF IMMUNOLOGY

Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12

(2009) M. Inui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The p85  Subunit of Class IA Phosphatidylinositol 3-Kinase Regulates the Expression of Multiple Genes Involved in Osteoclast Maturation and Migration

(2008) V. Munugalavadla et al.   MOLECULAR AND CELLULAR BIOLOGY

DAP12 Couples c-Fms Activation to the Osteoclast Cytoskeleton by Recruitment of Syk

(2008) Wei Zou et al.   MOLECULAR CELL