Molecular Mechanism of Substrate Specificity for Heparan Sulfate 2-O-Sulfotransferase

Heparan Sulfate Proteoglycans Containing a Glypican 5 Core and 2-O-Sulfo-iduronic Acid Function as Sonic Hedgehog Co-receptors to Promote Proliferation

(2013) Rochelle M. Witt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice

(2012) J. Axelsson et al.   BLOOD

Synthetic heparin

(2012) Robert J Linhardt et al.   CURRENT OPINION IN PHARMACOLOGY

Understanding the substrate specificity of the heparan sulfate sulfotransferases by an integrated biosynthetic and crystallographic approach

(2012) Jian Liu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Deciphering Mode of Action of Heparanase Using Structurally Defined Oligosaccharides

(2012) Sherket Peterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uncovering Biphasic Catalytic Mode of C5-epimerase in Heparan Sulfate Biosynthesis

(2012) Juzheng Sheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin

(2012) A. F. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemoenzymatic Synthesis of Homogeneous Ultralow Molecular Weight Heparins

(2011) Y. Xu et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Using Engineered 2-O-Sulfotransferase to Determine the Activity of Heparan Sulfate C5-epimerase and Its Mutants

(2010) Kai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemoenzymatic Design of Heparan Sulfate Oligosaccharides

(2010) Renpeng Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Lessons learned from the contamination of heparin

(2009) Haiying Liu et al.   NATURAL PRODUCT REPORTS

Solution Structures of Chemoenzymatically Synthesized Heparin and Its Precursors

(2008) Zhenqing Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis

(2008) H. N. Bethea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA