Protein Kinase Cα (PKCα) Regulates Bone Architecture and Osteoblast Activity
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Title
Protein Kinase Cα (PKCα) Regulates Bone Architecture and Osteoblast Activity
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 37, Pages 25509-25522
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2014-07-29
DOI
10.1074/jbc.m114.580365
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Note: Only part of the references are listed.- Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes
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- (2013) Christopher M. Williams et al. PLATELETS
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- (2012) L. K. Saxon et al. ENDOCRINOLOGY
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- (2012) Sara H Windahl et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2012) Behzad Javaheri et al. PLoS One
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- (2011) Moustapha Kassem et al. AGING CELL
- Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it
- (2011) Leanne K. Saxon et al. BONE
- Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading
- (2011) Xiaolin Tu et al. BONE
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- (2011) Kyu Sang Joeng et al. DEVELOPMENTAL BIOLOGY
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- (2010) Mary L Bouxsein et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2010) Roger MD Zebaze et al. LANCET
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- (2010) Ji Min Lee et al. MOLECULAR CELL
- Mechanical Stress Activates Smad Pathway through PKCδ to Enhance Interleukin-11 Gene Transcription in Osteoblasts
- (2010) Shinsuke Kido et al. PLoS One
- Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage
- (2010) P. K. Mistry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The clinical course of untreated Gaucher disease in 22 patients over 10 years: Hematological and skeletal manifestations
- (2009) Siavash Piran et al. BLOOD CELLS MOLECULES AND DISEASES
- Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro
- (2009) Liping Wang et al. BONE
- Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis
- (2009) James M. Haughian et al. INTERNATIONAL JOURNAL OF CANCER
- Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling
- (2009) Andrew Sunters et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- Stimulation of protein kinase C-α suppresses colon cancer cell proliferation by down-regulation of β-catenin
- (2009) Jungsug Gwak et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification
- (2009) Athanasia Spandidos et al. NUCLEIC ACIDS RESEARCH
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- (2009) Tommy Noh et al. PLoS One
- Protein kinase Cα: disease regulator and therapeutic target
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