The Centrosomal Adaptor TACC3 and the Microtubule Polymerase chTOG Interact via Defined C-terminal Subdomains in an Aurora-A Kinase-independent Manner

Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division

(2013) Harish C. Thakur et al.   BIOLOGICAL CHEMISTRY

Aurora A kinase and its substrate TACC3 are required for central spindle assembly

(2013) Antonios Lioutas et al.   EMBO REPORTS

Coordination of adjacent domains mediates TACC3–ch-TOG–clathrin assembly and mitotic spindle binding

(2013) Fiona E. Hood et al.   JOURNAL OF CELL BIOLOGY

A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells

(2013) R Yao et al.   ONCOGENE

Self-assembly and sorting of acentrosomal microtubules by TACC3 facilitate kinetochore capture during the mitotic spindle assembly

(2013) W. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules

(2012) Yirui Guo et al.   ACS Chemical Biology

SH3-mediated targeting of Wrch1/RhoU by multiple adaptor proteins

(2012) Sarah L. Risse et al.   BIOLOGICAL CHEMISTRY

Centrosome amplification in tumorigenesis

(2012) Simon J. Anderhub et al.   CANCER LETTERS

GF-15, a Novel Inhibitor of Centrosomal Clustering, Suppresses Tumor Cell Growth In Vitro and In Vivo

(2012) M. S. Raab et al.   CANCER RESEARCH

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Centrosomes, chromosome instability (CIN) and aneuploidy

(2012) Benjamin D Vitre et al.   CURRENT OPINION IN CELL BIOLOGY

Losing balance: the origin and impact of aneuploidy in cancer

(2012) Andrew J Holland et al.   EMBO REPORTS

Oncogenic FGFR3 gene fusions in bladder cancer

(2012) Sarah V. Williams et al.   HUMAN MOLECULAR GENETICS

A Clinical Overview of Centrosome Amplification in Human Cancers

(2012) Jason Yongsheng Chan   International Journal of Biological Sciences

Breaking the ties that bind: New advances in centrosome biology

(2012) Balca R. Mardin et al.   JOURNAL OF CELL BIOLOGY

The role of clathrin in mitotic spindle organisation

(2012) S. J. Royle   JOURNAL OF CELL SCIENCE

Never tear us apart - the importance of centrosome clustering

(2012) V. Marthiens et al.   JOURNAL OF CELL SCIENCE

DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis

(2012) Yu-Ting Yang et al.   NATURE NEUROSCIENCE

Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding

(2012) Yunhua Shi et al.   PROTEIN SCIENCE

Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

(2012) D. Singh et al.   SCIENCE

The Centrosome in Cells and Organisms

(2012) M. Bornens   SCIENCE

Cdh1 controls the stability of TACC3

(2011) Jen-Chong Jeng et al.   CELL CYCLE

Novel functions of endocytic player clathrin in mitosis

(2011) Wenxiang Fu et al.   CELL RESEARCH

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

(2011) Daniel G Booth et al.   EMBO JOURNAL

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

(2011) Lis Jakobsen et al.   EMBO JOURNAL

Centrosome clustering and chromosomal (in)stability: A matter of life and death

(2011) Alwin Krämer et al.   Molecular Oncology

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries

(2011) Erich A. Nigg et al.   NATURE CELL BIOLOGY

Disruption of Tacc3 function leads to in vivo tumor regression

(2011) R Yao et al.   ONCOGENE

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B

(2011) C. L. Partch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Centrosomes and cilia in human disease

(2011) Mónica Bettencourt-Dias et al.   TRENDS IN GENETICS

The centrosome and mitotic spindle apparatus in cancer and senescence

(2010) Stephan Schmidt et al.   CELL CYCLE

TACC3-TSC2 maintains nuclear envelope structure and controls cell division

(2010) Laia Gómez-Baldó et al.   CELL CYCLE

Proteomic and functional analysis of the mitotic Drosophila centrosome

(2010) Hannah Müller et al.   EMBO JOURNAL

Uncovering new substrates for Aurora A kinase

(2010) Teresa Sardon et al.   EMBO REPORTS

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

(2010) Beate Neumann et al.   NATURE

A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells

(2010) A B Fielding et al.   ONCOGENE

The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program

(2010) S Schmidt et al.   ONCOGENE

A small molecule accelerates neuronal differentiation in the adult rat

(2010) H. Wurdak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins

(2010) J. R. A. Hutchins et al.   SCIENCE

From Zero to Many: Control of Centriole Number in Development and Disease

(2009) Inês Cunha-Ferreira et al.   TRAFFIC

Centrosome function in cancer: guilty or innocent?

(2009) Deborah Zyss et al.   TRENDS IN CELL BIOLOGY

A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family

(2008) Alexander Eberth et al.   BIOCHEMICAL JOURNAL

XMAP215 Is a Processive Microtubule Polymerase

(2008) Gary J. Brouhard et al.   CELL

Centrosome Amplification Can Initiate Tumorigenesis in Flies

(2008) Renata Basto et al.   CELL

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

(2008) M. Kwon et al.   GENES & DEVELOPMENT

Xenopus TACC3/Maskin Is Not Required for Microtubule Stability but Is Required for Anchoring Microtubules at the Centrosome

(2008) Alison J. Albee et al.   MOLECULAR BIOLOGY OF THE CELL

The TACC proteins: TACC-ling microtubule dynamics and centrosome function

(2008) Isabel Peset et al.   TRENDS IN CELL BIOLOGY