Quantification of Mitochondrial Acetylation Dynamics Highlights Prominent Sites of Metabolic Regulation

Mitochondrial protein acetylation regulates metabolism

(2014) Kristin A. Anderson et al.   Essays in Biochemistry

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

(2013) Jeongsoon Park et al.   MOLECULAR CELL

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

(2013) M. J. Rardin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac mitochondrial matrix and respiratory complex protein phosphorylation

(2012) Raul Covian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1

(2012) Iain Scott et al.   BIOCHEMICAL JOURNAL

Metabolic inflexibility and protein lysine acetylation in heart mitochondria of a chronic model of Type 1 diabetes

(2012) Shraddha S. Vadvalkar et al.   BIOCHEMICAL JOURNAL

Systematic Functional Prioritization of Protein Posttranslational Modifications

(2012) Pedro Beltrao et al.   CELL

A Quantitative Map of the Liver Mitochondrial Phosphoproteome Reveals Posttranslational Control of Ketogenesis

(2012) Paul A. Grimsrud et al.   Cell Metabolism

Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance

(2012) Christopher B. Newgard   Cell Metabolism

Mitochondrial Protein Acylation and Intermediary Metabolism: Regulation by Sirtuins and Implications for Metabolic Disease

(2012) John C. Newman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin Catalysis and Regulation

(2012) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status

(2012) Wei Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic insights into the regulation of metabolic enzymes by acetylation

(2012) Yue Xiong et al.   JOURNAL OF CELL BIOLOGY

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Peripheral Effects of FAAH Deficiency on Fuel and Energy Homeostasis: Role of Dysregulated Lysine Acetylation

(2012) Bhavapriya Vaitheesvaran et al.   PLoS One

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondrial sirtuins: regulators of protein acylation and metabolism

(2012) Wenjuan He et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns

(2012) Alicia Lundby et al.   Cell Reports

Insulin resistance and the metabolism of branched-chain amino acids in humans

(2011) María M. Adeva et al.   AMINO ACIDS

Metabolic Flux and the Regulation of Mammalian Cell Growth

(2011) Jason W. Locasale et al.   Cell Metabolism

Regulation and protection of mitochondrial physiology by sirtuins

(2011) Claudia V. Pereira et al.   MITOCHONDRION

SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome

(2011) Matthew D. Hirschey et al.   MOLECULAR CELL

Gas-phase purification enables accurate, multiplexed proteome quantification with isobaric tagging

(2011) Craig D Wenger et al.   NATURE METHODS

Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

(2011) Lydia W. S. Finley et al.   PLoS One

High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria

(2011) George W. Rogers et al.   PLoS One

COMPASS: A suite of pre- and post-search proteomics software tools for OMSSA

(2011) Craig D. Wenger et al.   PROTEOMICS

Metabolic syndrome, age-associated neuroendocrine disorders, and dysregulation of tryptophan-kynurenine metabolism

(2010) Gregory F. Oxenkrug   Annals of the New York Academy of Sciences

Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

(2010) Agnieszka A. Kendrick et al.   BIOCHEMICAL JOURNAL

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

(2010) Hyun-Seok Kim et al.   CANCER CELL

SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production

(2010) Tadahiro Shimazu et al.   Cell Metabolism

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity

(2010) Jianjun Bao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Evolutionary Constraints of Phosphorylation in Eukaryotes, Prokaryotes, and Mitochondria

(2010) Florian Gnad et al.   MOLECULAR & CELLULAR PROTEOMICS

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Increased Mitochondrial Oxidative Phosphorylation in the Liver Is Associated With Obesity and Insulin Resistance

(2010) David A. Buchner et al.   Obesity

Rise of the Rival

(2010) A. Norvell et al.   SCIENCE

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Regulation of intermediary metabolism by protein acetylation

(2010) Kun-Liang Guan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

(2009) Huseyin Cimen et al.   BIOCHEMISTRY

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice

(2009) Enpeng Zhao et al.   MAMMALIAN GENOME

A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation

(2009) Heinz Neumann et al.   MOLECULAR CELL

Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II

(2008) Qian Han et al.   BIOSCIENCE REPORTS

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility

(2008) M. P. Keller et al.   GENOME RESEARCH

Genetically encoding Nε-acetyllysine in recombinant proteins

(2008) Heinz Neumann et al.   Nature Chemical Biology

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative phosphoproteomics reveals evolutionary and functional conservation of phosphorylation across eukaryotes

(2008) Jos Boekhorst et al.   GENOME BIOLOGY

Enhanced Bacterial Protein Expression During Auto-Induction Obtained by Alteration of Lac Repressor Dosage and Medium Composition

(2007) Paul G. Blommel et al.   BIOTECHNOLOGY PROGRESS