Metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine by Mitochondrion-targeted Cytochrome P450 2D6

Mitochondria-Targeted Small Molecule Therapeutics and Probes

(2011) Robin A.J. Smith et al.   ANTIOXIDANTS & REDOX SIGNALING

Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals

(2011) Narayan G. Avadhani et al.   FEBS Journal

The neuroprotective enzyme CYP2D6 increases in the brain with age and is lower in Parkinson's disease patients

(2011) Amandeep Mann et al.   NEUROBIOLOGY OF AGING

Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicity

(2010) Michelle C Sangar et al.   Expert Opinion on Drug Metabolism & Toxicology

Mitochondria-targeted Cytochrome P450 2E1 Induces Oxidative Damage and Augments Alcohol-mediated Oxidative Stress

(2010) Seema Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function

(2009) F. Dutheil et al.   DRUG METABOLISM AND DISPOSITION

In a flurry of PINK, mitochondrial bioenergetics takes a leading role in Parkinson's disease

(2009) Anne N. Murphy   EMBO Molecular Medicine

Human liver mitochondrial cytochrome P450 2D6 - individual variations and implications in drug metabolism

(2009) Michelle Cook Sangar et al.   FEBS Journal

Identification of genetic variants of human cytochrome P450 2D6 with impaired mitochondrial targeting

(2009) Michelle Cook Sangar et al.   MOLECULAR GENETICS AND METABOLISM

Genetic predisposition to Parkinsonʼs disease: CYP2D6 and HFE in the Faroe Islands

(2009) Jónrit Halling et al.   Pharmacogenetics and Genomics

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models of Parkinson’s disease progression

(2008) Gloria E. Meredith et al.   ACTA NEUROPATHOLOGICA

Knock-In Mouse Lines Expressing either Mitochondrial or Microsomal CYP1A1: Differing Responses to Dietary Benzo[a]pyrene as Proof of Principle

(2008) H. Dong et al.   MOLECULAR PHARMACOLOGY