The Lhs1/GRP170 Chaperones Facilitate the Endoplasmic Reticulum-associated Degradation of the Epithelial Sodium Channel

Cleaning Up: ER-Associated Degradation to the Rescue

(2012) Jeffrey L. Brodsky   CELL

Epithelial Na+ channel regulation by cytoplasmic and extracellular factors

(2012) Ossama B. Kashlan et al.   EXPERIMENTAL CELL RESEARCH

The Endosomal Protein-Sorting Receptor Sortilin Has a Role in Trafficking  -1 Antitrypsin

(2012) C. L. Gelling et al.   GENETICS

Hsp70 Promotes Epithelial Sodium Channel Functional Expression by Increasing Its Association with Coat Complex II and Its Exit from Endoplasmic Reticulum

(2012) Rebecca A. Chanoux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FK506 Binding Protein 8 Peptidylprolyl Isomerase Activity Manages a Late Stage of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Folding and Stability

(2012) Darren M. Hutt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A gating motif in the translocation channel sets the hydrophobicity threshold for signal sequence function

(2012) Steven F. Trueman et al.   JOURNAL OF CELL BIOLOGY

The Delicate Balance Between Secreted Protein Folding and Endoplasmic Reticulum-Associated Degradation in Human Physiology

(2012) Christopher J. Guerriero et al.   PHYSIOLOGICAL REVIEWS

Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis

(2012) Daniel N. Hebert et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structural analysis of the Sil1–Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor

(2011) Ming Yan et al.   BIOCHEMICAL JOURNAL

The Thiazide-sensitive NaCl Cotransporter Is Targeted for Chaperone-dependent Endoplasmic Reticulum-associated Degradation

(2011) Patrick G. Needham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport

(2011) Rama Soundararajan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Protein disulfide isomerases contribute differentially to the endoplasmic reticulum–associated degradation of apolipoprotein B and other substrates

(2011) Sarah Grubb et al.   MOLECULAR BIOLOGY OF THE CELL

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

Protein quality control in the ER: balancing the ubiquitin checkbook

(2011) Jasper H.L. Claessen et al.   TRENDS IN CELL BIOLOGY

CFTR: folding, misfolding and correcting the ΔF508 conformational defect

(2011) Gergely L. Lukacs et al.   TRENDS IN MOLECULAR MEDICINE

Participation of lectin chaperones and thiol oxidoreductases in protein folding within the endoplasmic reticulum

(2010) Lori A Rutkevich et al.   CURRENT OPINION IN CELL BIOLOGY

Cys Palmitoylation of the β Subunit Modulates Gating of the Epithelial Sodium Channel

(2010) Gunhild M. Mueller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Epithelial Sodium Channels and Their Regulators in Hypertension

(2010) Rama Soundararajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp90 Is Required for Transfer of the Cholera Toxin A1 Subunit from the Endoplasmic Reticulum to the Cytosol

(2010) Michael Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Endoplasmic Reticulum Grp170 Acts as a Nucleotide Exchange Factor of Hsp70 via a Mechanism Similar to That of the Cytosolic Hsp110

(2010) Claes Andréasson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions between Kar2p and Its Nucleotide Exchange Factors Sil1p and Lhs1p Are Mechanistically Distinct

(2010) Sarah J. Hale et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Endoplasmic Reticulum–associated Degradation of the Epithelial Sodium Channel Requires a Unique Complement of Molecular Chaperones

(2010) Teresa M. Buck et al.   MOLECULAR BIOLOGY OF THE CELL

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cotranslational and Posttranslational N-Glycosylation of Polypeptides by Distinct Mammalian OST Isoforms

(2009) Catalina Ruiz-Canada et al.   CELL

Nucleotide Binding by Lhs1p Is Essential for Its Nucleotide Exchange Activity and for Functionin Vivo

(2009) Jeanine de Keyzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

(2009) Simone Clerc et al.   JOURNAL OF CELL BIOLOGY

N-glycan structures: recognition and processing in the ER

(2009) Markus Aebi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structural Basis for the Cooperation of Hsp70 and Hsp110 Chaperones in Protein Folding

(2008) Sigrun Polier et al.   CELL

Dissecting the ER-Associated Degradation of a Misfolded Polytopic Membrane Protein

(2008) Kunio Nakatsukasa et al.   CELL

Mechanisms of ENaC Regulation and Clinical Implications

(2008) V. Bhalla et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

ERdj4 and ERdj5 Are Required for Endoplasmic Reticulum-associated Protein Degradation of Misfolded Surfactant Protein C

(2008) Mei Dong et al.   MOLECULAR BIOLOGY OF THE CELL

Defining the Glycan Destruction Signal for Endoplasmic Reticulum-Associated Degradation

(2008) Erin M. Quan et al.   MOLECULAR CELL

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY