Phosphorylation of KRAB-associated Protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by Nuclear Tyrosine Kinases Inhibits the Association of KAP1 and Heterochromatin Protein 1α (HP1α) with Heterochromatin

Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response

(2012) Dong-Hyun Lee et al.   EMBO JOURNAL

c-Src but Not Fyn Promotes Proper Spindle Orientation in Early Prometaphase

(2012) Yuji Nakayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear ErbB4 signaling through H3K9me3 is antagonized by EGFR-activated c-Src

(2012) K. Ishibashi et al.   JOURNAL OF CELL SCIENCE

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

Trim28 Is Required for Epigenetic Stability During Mouse Oocyte to Embryo Transition

(2012) D. M. Messerschmidt et al.   SCIENCE

Nuclear c-Abl-mediated tyrosine phosphorylation induces chromatin structural changes through histone modifications that include H4K16 hypoacetylation

(2011) Kazumasa Aoyama et al.   EXPERIMENTAL CELL RESEARCH

KAP1 Protein: An Enigmatic Master Regulator of the Genome

(2011) Sushma Iyengar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HP1α recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair

(2011) Céline Baldeyron et al.   JOURNAL OF CELL BIOLOGY

The ATM Substrate KAP1 Controls DNA Repair in Heterochromatin: Regulation by HP1 Proteins and Serine 473/824 Phosphorylation

(2011) D. White et al.   MOLECULAR CANCER RESEARCH

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response

(2011) Aaron A Goodarzi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cost-effective gene transfection by DNA compaction at pH 4.0 using acidified, long shelf-life polyethylenimine

(2010) Yasunori Fukumoto et al.   CYTOTECHNOLOGY

HP1: Heterochromatin binding proteins working the genome

(2010) Weihua Zeng et al.   Epigenetics

The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis

(2010) Barbara Herkert et al.   JOURNAL OF CELL BIOLOGY

The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association

(2010) Y. Obata et al.   JOURNAL OF CELL SCIENCE

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

(2010) Angela T. Noon et al.   NATURE CELL BIOLOGY

Tyrosine phosphorylation: thirty years and counting

(2009) Tony Hunter   CURRENT OPINION IN CELL BIOLOGY

Nuclear localization of Src-family tyrosine kinases is required for growth factor-induced euchromatinization

(2009) Akinori Takahashi et al.   EXPERIMENTAL CELL RESEARCH

Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway

(2009) Yuji Nakayama et al.   EXPERIMENTAL CELL RESEARCH

Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain

(2009) I. Sato et al.   JOURNAL OF CELL SCIENCE

Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling

(2009) Ramars Amanchy et al.   Molecular Oncology

JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

(2009) Mark A. Dawson et al.   NATURE

Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1

(2008) Chiung-Wen Chang et al.   BMC MOLECULAR BIOLOGY

Role of Src-family kinases in formation of the cortical actin cap at the dorsal cell surface

(2008) Takahisa Kuga et al.   EXPERIMENTAL CELL RESEARCH

Nuclear localization of Lyn tyrosine kinase mediated by inhibition of its kinase activity

(2008) Kikuko Ikeda et al.   EXPERIMENTAL CELL RESEARCH

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL