Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) Protein Is Involved in Centrosome Separation through the Regulation of NIMA (Never In Mitosis Gene A)-related Kinase 2 (NEK2) Protein Activity

CIP2A expression is elevated in cervical cancer

(2017) Lisa P. Huang et al.   Cancer Biomarkers

NEK2 phosphorylation antagonizes the microtubule stabilizing activity of centrobin

(2013) Joonhyun Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NEK2 Induces Drug Resistance Mainly through Activation of Efflux Drug Pumps and Is Associated with Poor Prognosis in Myeloma and Other Cancers

(2013) Wen Zhou et al.   CANCER CELL

EGF-Induced Centrosome Separation Promotes Mitotic Progression and Cell Survival

(2013) Balca R. Mardin et al.   DEVELOPMENTAL CELL

CIP2A expression is associated with altered expression of epithelial–mesenchymal transition markers and predictive of poor prognosis in pancreatic ductal adenocarcinoma

(2013) Lei Wang et al.   TUMOR BIOLOGY

Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1

(2013) Anni Laine et al.   Cancer Discovery

Expression and prognostic significance of CIP2A mRNA in hepatocellular carcinoma and nontumoral liver tissues

(2012) Pinzhu Huang et al.   BIOMARKERS

CIP2A overexpression is associated with c-Myc expression in colorectal cancer

(2012) Camilla Böckelman et al.   CANCER BIOLOGY & THERAPY

Condensin, Chromatin Crossbarring and Chromosome Condensation

(2012) Rahul Thadani et al.   CURRENT BIOLOGY

CIP2A Is Highly Expressed in Hepatocellular Carcinoma and Predicts Poor Prognosis

(2012) Hui He et al.   DIAGNOSTIC MOLECULAR PATHOLOGY

CIP2A Is a Predictor of Poor Prognosis in Colon Cancer

(2012) Hao-Wei Teng et al.   JOURNAL OF GASTROINTESTINAL SURGERY

CIP2A is a predictor of survival and a novel therapeutic target in bladder urothelial cell carcinoma

(2012) Yijun Xue et al.   MEDICAL ONCOLOGY

CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes

(2012) M Niemelä et al.   ONCOGENE

CIP2A-mediated Akt activation plays a role in bortezomib-induced apoptosis in head and neck squamous cell carcinoma cells

(2012) Yu-Chin Lin et al.   ORAL ONCOLOGY

CIP2A Promotes Proliferation of Spermatogonial Progenitor Cells and Spermatogenesis in Mice

(2012) Sami Ventelä et al.   PLoS One

CIP2A is overexpressed in human ovarian cancer and regulates cell proliferation and apoptosis

(2012) Yuanyuan Fang et al.   TUMOR BIOLOGY

CIP2A protein expression in high-grade, high-stage bladder cancer

(2012) Lisa P. Huang et al.   Cancer Medicine

Prognostic role of CIP2A expression in serous ovarian cancer

(2011) C Böckelman et al.   BRITISH JOURNAL OF CANCER

Expression of CIP2A in renal cell carcinomas correlates with tumour invasion, metastasis and patients’ survival

(2011) J Ren et al.   BRITISH JOURNAL OF CANCER

High CIP2A immunoreactivity is an independent prognostic indicator in early-stage tongue cancer

(2011) C Böckelman et al.   BRITISH JOURNAL OF CANCER

Increase in CIP2A expression is associated with doxorubicin resistance

(2011) Yeon A. Choi et al.   FEBS LETTERS

Cancerous inhibitor of protein phosphatase 2A is overexpressed in cervical cancer and upregulated by human papillomavirus 16 E7 oncoprotein

(2011) Juan Liu et al.   GYNECOLOGIC ONCOLOGY

CIP2A is over-expressed in acute myeloid leukaemia and associated with HL60 cells proliferation and differentiation

(2011) J. WANG et al.   International Journal of Laboratory Hematology

Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint

(2011) Randy Wei et al.   MOLECULAR BIOLOGY OF THE CELL

Timing of centrosome separation is important for accurate chromosome segregation

(2011) William T. Silkworth et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation

(2011) D P Mathiasen et al.   ONCOGENE

ETS1 Mediates MEK1/2-Dependent Overexpression of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) in Human Cancer Cells

(2011) Anchit Khanna et al.   PLoS One

Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer

(2011) Liang Ma et al.   PLoS One

CIP2A is Overexpressed in Non-Small Cell Lung Cancer and Correlates with Poor Prognosis

(2010) Qian-Ze Dong et al.   ANNALS OF SURGICAL ONCOLOGY

CIP2A expression and localization in oral carcinoma and dysplasia

(2010) Joseph Katz et al.   CANCER BIOLOGY & THERAPY

CIP2A expression is increased in prostate cancer

(2010) Markku H Vaarala et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

KIAA1524: A novel MLL translocation partner in acute myeloid leukemia

(2010) Eva A. Coenen et al.   LEUKEMIA RESEARCH

CIP2A is overexpressed in esophageal squamous cell carcinoma

(2010) Wei Qu et al.   MEDICAL ONCOLOGY

Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction

(2010) Balca R. Mardin et al.   NATURE CELL BIOLOGY

CIP2A Is Associated with Human Breast Cancer Aggressivity

(2009) C. Come et al.   CLINICAL CANCER RESEARCH

MYC-Dependent Regulation and Prognostic Role of CIP2A in Gastric Cancer

(2009) Anchit Khanna et al.   JNCI-Journal of the National Cancer Institute

CIP2A Is Overexpressed in Gastric Cancer and Its Depletion Leads to Impaired Clonogenicity, Senescence, or Differentiation of Tumor Cells

(2008) W. Li et al.   CLINICAL CANCER RESEARCH

Insights into the Conformational Variability and Regulation of Human Nek2 Kinase

(2008) Isaac Westwood et al.   JOURNAL OF MOLECULAR BIOLOGY

The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability

(2008) J Du et al.   ONCOGENE

-Catenin is a Nek2 substrate involved in centrosome separation

(2007) S. Bahmanyar et al.   GENES & DEVELOPMENT