Model of Tryptophan Metabolism, Readily Scalable Using Tissue-specific Gene Expression Data

Effect of substrate competition in kinetic models of metabolic networks

(2013) Sascha Schäuble et al.   FEBS LETTERS

Improving metabolic flux predictions using absolute gene expression data

(2012) Dave Lee et al.   BMC Systems Biology

Targeting Kynurenine 3-Monooxygenase (KMO): Implications for Therapy in Huntingtons Disease

(2012) Mathuravani A. Thevandavakkam et al.   CNS & Neurological Disorders-Drug Targets

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-  Signaling Pathway in Human Glioblastoma

(2011) M. Grzmil et al.   CANCER RESEARCH

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

(2011) Daniel Zwilling et al.   CELL

The Kynurenine Pathway Modulates Neurodegeneration in a Drosophila Model of Huntington's Disease

(2011) Susanna Campesan et al.   CURRENT BIOLOGY

Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators

(2011) Eduard Dolušić et al.   JOURNAL OF MEDICINAL CHEMISTRY

Kynurenines in Parkinson’s disease: therapeutic perspectives

(2011) Dénes Zádori et al.   JOURNAL OF NEURAL TRANSMISSION

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Reorganizing the protein space at the Universal Protein Resource (UniProt)

(2011)   NUCLEIC ACIDS RESEARCH

Kynurenines, neurodegeneration and Alzheimer’s disease

(2010) Zsigmond Tamas Kincses et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

BRENDA, the enzyme information system in 2011

(2010) M. Scheer et al.   NUCLEIC ACIDS RESEARCH

Induction of IDO by Bacille Calmette-Guerin Is Responsible for Development of Murine Depressive-Like Behavior

(2009) J. C. O'Connor et al.   JOURNAL OF IMMUNOLOGY

KEGG for representation and analysis of molecular networks involving diseases and drugs

(2009) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry

(2009) Øivind Midttun et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

A comprehensive functional analysis of tissue specificity of human gene expression

(2008) Zoltan Dezso et al.   BMC BIOLOGY

Discovery and Characterization of Novel Tryptophan Hydroxylase Inhibitors That Selectively Inhibit Serotonin Synthesis in the Gastrointestinal Tract

(2008) Q. Liu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A new strategy for assessing sensitivities in biochemical models

(2008) S. Sahle et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES