Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes

Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

(2011) Susan E. Tsutakawa et al.   CELL

Neutralizing Mutations of Carboxylates That Bind Metal 2 in T5 Flap Endonuclease Result in an Enzyme That Still Requires Two Metal Ions

(2011) Christopher G. Tomlinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases

(2011) Jane A. Grasby et al.   TRENDS IN BIOCHEMICAL SCIENCES

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of the endonuclease IV homologue fromThermotoga maritimain the presence of active-site divalent metal ions

(2010) Stephen J. Tomanicek et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Understanding the Effect of Magnesium Ion Concentration on the Catalytic Activity of Ribonuclease H through Computation: Does a Third Metal Binding Site Modulate Endonuclease Catalysis?

(2010) Ming-Hsun Ho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Microbial metalloproteomes are largely uncharacterized

(2010) Aleksandar Cvetkovic et al.   NATURE

Flipping of alkylated DNA damage bridges base and nucleotide excision repair

(2009) Julie L. Tubbs et al.   NATURE

Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair

(2009) Bjørn Dalhus et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

(2009) T. Barnes et al.   NUCLEIC ACIDS RESEARCH

Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family

(2009) V. M. Castillo-Acosta et al.   NUCLEIC ACIDS RESEARCH

Enzymatic Mechanism of Human Apurinic/Apyrimidinic Endonuclease against a THF AP Site Model Substrate†

(2008) Sophia T. Mundle et al.   BIOCHEMISTRY

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

(2008) R. Scott Williams et al.   CELL

Unusual Role of a Cysteine Residue in Substrate Binding and Activity of Human AP-Endonuclease 1

(2008) Anil K. Mantha et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of Mg2+Binding to the DNA Repair Protein Apurinic/Apyrimidic Endonuclease 1 via Solid-State25Mg NMR Spectroscopy

(2008) A. S. Lipton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease

(2008) M.M. Georgiadis et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

An equivalent metal ion in one- and two-metal-ion catalysis

(2008) Wei Yang   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA apurinic-apyrimidinic site binding and excision by endonuclease IV

(2008) Elsa D Garcin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY