Smoothened Oligomerization/Higher Order Clustering in Lipid Rafts Is Essential for High Hedgehog Activity Transduction

The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation

(2012) C. E. Carroll et al.   DEVELOPMENT

Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus

(2011) Yanyan Zhang et al.   CELL RESEARCH

The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation

(2011) Q. Shi et al.   DEVELOPMENT

Mechanisms and functions of Hedgehog signalling across the metazoa

(2011) Philip W. Ingham et al.   NATURE REVIEWS GENETICS

Sonic Hedgehog Activates the GTPases Rac1 and RhoA in a Gli-Independent Manner Through Coupling of Smoothened to Gi Proteins

(2011) A. H. Polizio et al.   Science Signaling

Mechanism and evolution of cytosolic Hedgehog signal transduction

(2010) C. W. Wilson et al.   DEVELOPMENT

Ihog and Boi are essential for Hedgehog signaling in Drosophila

(2010) Darius Camp et al.   Neural Development

The differential protein and lipid compositions of noncaveolar lipid microdomains and caveolae

(2009) Yao Yao et al.   CELL RESEARCH

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL