Histone Deacetylase 7 Promotes Toll-like Receptor 4-dependent Proinflammatory Gene Expression in Macrophages

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

HDAC7 Is a Repressor of Myeloid Genes Whose Downregulation Is Required for Transdifferentiation of Pre-B Cells into Macrophages

(2013) Bruna Barneda-Zahonero et al.   PLoS Genetics

Endothelin-1 and the kidney - beyond BP

(2012) Neeraj Dhaun et al.   BRITISH JOURNAL OF PHARMACOLOGY

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomarkers of endothelial dysfunction: can they help us deciphering systemic inflammation and sepsis?

(2011) Patrick Paulus et al.   BIOMARKERS

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation

(2011) S. E. Mullican et al.   GENES & DEVELOPMENT

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Endothelin 1 contributes to the effect of transforming growth factor β1 on wound repair and skin fibrosis

(2010) David Lagares et al.   ARTHRITIS AND RHEUMATISM

Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression

(2010) Catherine Aude-Garcia et al.   BIOCHEMICAL JOURNAL

Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

(2010) T. Roger et al.   BLOOD

At the heart of tissue: endothelin system and end-organ damage

(2010) Marc Iglarz et al.   CLINICAL SCIENCE

The clinical development of histone deacetylase inhibitors as targeted anticancer drugs

(2010) Paul A Marks   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

(2010) Maria A. Halili et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis

(2010) Q. Huang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells

(2010) W Song et al.   LEUKEMIA

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Targeting Toll-like receptors: emerging therapeutics?

(2010) Elizabeth J. Hennessy et al.   NATURE REVIEWS DRUG DISCOVERY

Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis

(2010) Nobuyo Higashi-Kuwata et al.   ARTHRITIS RESEARCH & THERAPY

Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis

(2009) Hossein Hemmatazad et al.   ARTHRITIS AND RHEUMATISM

Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins

(2009) Susan Carpenter et al.   BIOCHEMICAL JOURNAL

Diphenylmethylene hydroxamic acids as selective class IIa histone deacetylase inhibitors

(2009) Pierre Tessier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Histone Deacetylase Inhibitors In Inflammatory Disease

(2009) Maria Halili et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

TIR-containing adaptors in Toll-like receptor signalling

(2009) Kristie A. Jenkins et al.   CYTOKINE

Inhibition of HDAC9 Increases T Regulatory Cell Function and Prevents Colitis in Mice

(2009) Edwin F. de Zoeten et al.   GASTROENTEROLOGY

Splicing of HDAC7 modulates the SRF-myocardin complex during stem-cell differentiation towards smooth muscle cells

(2009) A. Margariti et al.   JOURNAL OF CELL SCIENCE

Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis

(2009) Reiji Higashiyama et al.   Modern Rheumatology

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer

(2009) L. A. J. O'Neill et al.   PHARMACOLOGICAL REVIEWS

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling

(2008) Wangsen Cao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blocking TH 17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo

(2008) Daniela Bosisio et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

(2008) Alejandro Villagra et al.   NATURE IMMUNOLOGY