Molecular Architecture of a Sodium Channel S6 Helix

A new Nav1.7 mutation in an erythromelalgia patient

(2013) Mark Estacion et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy

(2012) Chongyang Han et al.   BRAIN

The conformational shifts of the voltage sensing domains between NavRh and NavAb

(2012) Xu Zhang et al.   CELL RESEARCH

The NaV1.7 sodium channel: from molecule to man

(2012) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

Nav1.7-related small fiber neuropathy: Impaired slow-inactivation and DRG neuron hyperexcitability

(2012) C. Han et al.   NEUROLOGY

Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons

(2012) Michael S. Minett et al.   Nature Communications

Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Nav1.7 mutant channel

(2012) Yang Yang et al.   Nature Communications

Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing

(2012) Emily C. McCusker et al.   Nature Communications

Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy

(2011) Catharina G. Faber et al.   ANNALS OF NEUROLOGY

Deletion mutation of sodium channel NaV1.7 in inherited erythromelalgia: enhanced slow inactivation modulates dorsal root ganglion neuron hyperexcitability

(2011) X. Cheng et al.   BRAIN

Molecular Basis and Structural Insight of Vascular KATPChannel Gating byS-Glutathionylation

(2011) Yang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Atomic-Level Protein Structure Refinement Using Fragment-Guided Molecular Dynamics Conformation Sampling

(2011) Jian Zhang et al.   STRUCTURE

Sodium Channels in Normal and Pathological Pain

(2010) Sulayman D. Dib-Hajj et al.   Annual Review of Neuroscience

GPCRRD: G protein-coupled receptor spatial restraint database for 3D structure modeling and function annotation

(2010) Jian Zhang et al.   BIOINFORMATICS

A Molecular Switch between the Outer and the Inner Vestibules of the Voltage-gated Na+Channel

(2010) Touran Zarrabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Can robots patch-clamp as well as humans? Characterization of a novel sodium channel mutation

(2010) M. Estacion et al.   JOURNAL OF PHYSIOLOGY-LONDON

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Molecular determinants of coupling between the domain III voltage sensor and pore of a sodium channel

(2010) Yukiko Muroi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Novel Side-Chain Orientation Dependent Potential Derived from Random-Walk Reference State for Protein Fold Selection and Structure Prediction

(2010) Jian Zhang et al.   PLoS One

A Pore-blocking Hydrophobic Motif at the Cytoplasmic Aperture of the Closed-state Nav1.7 Channel Is Disrupted by the Erythromelalgia-associated F1449V Mutation

(2008) Angelika Lampert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paroxysmal Extreme Pain Disorder M1627K Mutation in Human Nav1.7 Renders DRG Neurons Hyperexcitable

(2008) Sulayman D Dib-Hajj et al.   Molecular Pain