The Arrestin-selective Angiotensin AT1Receptor Agonist [Sar1,Ile4,Ile8]-AngII Negatively Regulates Bradykinin B2Receptor Signaling via AT1-B2Receptor Heterodimers

A High-Content, Live-Cell, and Real-Time Approach to the Quantitation of Ligand-Induced β-Arrestin2 and Class A/Class B GPCR Mobilization

(2013) Anthony P. Leonard et al.   MICROSCOPY AND MICROANALYSIS

TRV120027, a Novel β-Arrestin Biased Ligand at the Angiotensin II Type I Receptor, Unloads the Heart and Maintains Renal Function When Added to Furosemide in Experimental Heart Failure

(2012) Guido Boerrigter et al.   Circulation-Heart Failure

Gene expression profiling in glomeruli of diabetic nephropathy rat

(2012) Qian Zhang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity

(2012) Aude Saulière et al.   Nature Chemical Biology

Global Renal Gene Expression Profiling Analysis in B2-Kinin Receptor Null Mice: Impact of Diabetes

(2012) Miran A. Jaffa et al.   PLoS One

RAS-Mediated Adaptive Mechanisms in Cardiovascular Tissues: Confounding Factors of RAS Blockade Therapy and Alternative Approaches

(2012) Rukhsana Gul et al.   CardioRenal Medicine

A cleavable signal peptide enhances cell surface delivery and heterodimerization of Cerulean-tagged angiotensin II AT1 and bradykinin B2 receptor

(2011) Ursula Quitterer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cardiorenal Actions of TRV120027, a Novel ß-Arrestin–Biased Ligand at the Angiotensin II Type I Receptor, in Healthy and Heart Failure Canines

(2011) Guido Boerrigter et al.   Circulation-Heart Failure

Angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and combined therapy in patients with micro- and macroalbuminuria and other cardiovascular risk factors: a systematic review of randomized controlled trials

(2011) A. Maione et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery

(2010) T. Kenakin et al.   PHARMACOLOGICAL REVIEWS

The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling

(2010) Marie Mi Bonde et al.   REGULATORY PEPTIDES

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway

(2008) B ZIMMERMAN et al.   CELLULAR SIGNALLING

Lack of Evidence for AT1R/B2R Heterodimerization in COS-7, HEK293, and NIH3T3 Cells

(2008) Jakob L. Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional interactions between 7TM receptors in the Renin-Angiotensin System—Dimerization or crosstalk?

(2008) Christina Lyngsø et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Angiotensin II type 1 receptor expression is increased via 12-lipoxygenase in high glucose-stimulated glomerular cells and type 2 diabetic glomeruli

(2008) Z.-G. Xu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Assembly, activation, and physiologic influence of the plasma kallikrein/kinin system

(2007) Alvin H. Schmaier   INTERNATIONAL IMMUNOPHARMACOLOGY