An Antedrug of the CXCL12 Neutraligand Blocks Experimental Allergic Asthma without Systemic Effect in Mice

CXCL12/CXCR4-Axis Dysfunctions: Markers of the Rare Immunodeficiency Disorder WHIM Syndrome

(2013) Françoise Bachelerie   DISEASE MARKERS

Proper desensitization of CXCR4 is required for lymphocyte development and peripheral compartmentalization in mice

(2012) K. Balabanian et al.   BLOOD

The Chemokine CXCL12 Is Essential for the Clearance of the Filaria Litomosoides sigmodontis in Resistant Mice

(2012) Tiffany Bouchery et al.   PLoS One

C-Kit–Positive Cells Accumulate in Remodeled Vessels of Idiopathic Pulmonary Arterial Hypertension

(2011) David Montani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome

(2011) D. H. McDermott et al.   BLOOD

Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo

(2011) Vincent Gasparik et al.   ACS Medicinal Chemistry Letters

The CXCR4 Antagonist AMD3100 Has Dual Effects on Survival and Proliferation of Myeloma CellsIn Vitro

(2011) Ha-Yon Kim et al.   Cancer Research and Treatment

A Pivotal Role for CXCL12 Signaling in HPV-Mediated Transformation of Keratinocytes: Clues to Understanding HPV-Pathogenesis in WHIM Syndrome

(2010) Ken Y.C. Chow et al.   Cell Host & Microbe

Chemokine (C-X-C Motif) Ligand 12/Stromal Cell-Derived Factor-1 Is Associated With Leukocyte Recruitment in Asthma

(2010) María Cristina Negrete-García et al.   CHEST

Cancer and Inflammation: Implications for Pharmacology and Therapeutics

(2010) F Balkwill et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

AMD3100 is a potent antagonist at CXCR4R334X, a hyperfunctional mutant chemokine receptor and cause of WHIM syndrome

(2010) David H. McDermott et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Neutralizing endogenous chemokines with small molecules

(2010) Jean-Luc Galzi et al.   PHARMACOLOGY & THERAPEUTICS

CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling

(2009) A. Levoye et al.   BLOOD

The CXCL12 (SDF-1)/CXCR4 Axis Is Essential for the Development of Renal Vasculature

(2009) Y. Takabatake et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

AMD3100 Is a CXCR7 Ligand with Allosteric Agonist Properties

(2009) I. Kalatskaya et al.   MOLECULAR PHARMACOLOGY

New Macrocyclic Amines Showing Activity as HIV Entry Inhibitors Against Wild Type and Multi-Drug Resistant Viruses

(2009) Stefano Rusconi et al.   MOLECULES

Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues

(2008) K M Waldhauser et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synthesis and Pharmacology of Anti-Inflammatory Steroidal Antedrugs

(2008) M. Omar F. Khan et al.   CHEMICAL REVIEWS

Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice

(2008) Han Gerrits et al.   GENESIS

Small Neutralizing Molecules to Inhibit Actions of the Chemokine CXCL12

(2008) Muriel Hachet-Haas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuation of Obliterative Bronchiolitis by a CXCR4 Antagonist in the Murine Heterotopic Tracheal Transplant Model

(2008) Jianguo Xu et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION