Direct Gating of ATP-activated Ion Channels (P2X2 Receptors) by Lipophilic Attachment at the Outer End of the Second Transmembrane Domain

GABAAreceptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites

(2013) Cecilia M. Borghese et al.   JOURNAL OF NEUROCHEMISTRY

Structural Determinants of Specific Lipid Binding to Potassium Channels

(2013) Markus Weingarth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mutation of the ATP-gated P2X2 receptor leads to progressive hearing loss and increased susceptibility to noise

(2013) D. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiscale Simulations Reveal Conserved Patterns of Lipid Interactions with Aquaporins

(2013) Phillip J. Stansfeld et al.   STRUCTURE

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

(2012) Motoyuki Hattori et al.   NATURE

Neuromodulation by Extracellular ATP and P2X Receptors in the CNS

(2012) Baljit S. Khakh et al.   NEURON

From Coarse Grained to Atomistic: A Serial Multiscale Approach to Membrane Protein Simulations

(2011) Phillip J. Stansfeld et al.   Journal of Chemical Theory and Computation

Ion access pathway to the transmembrane pore in P2X receptor channels

(2011) Toshimitsu Kawate et al.   JOURNAL OF GENERAL PHYSIOLOGY

Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors)

(2011) D. S. K. Samways et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New structure enlivens interest in P2X receptors

(2010) Liam E. Browne et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Pore-opening mechanism in trimeric P2X receptor channels

(2010) Mufeng Li et al.   Nature Communications

Polar Residues in the Second Transmembrane Domain of the Rat P2X2 Receptor That Affect Spontaneous Gating, Unitary Conductance, and Rectification

(2009) L. Cao et al.   JOURNAL OF NEUROSCIENCE

Dynamic aspects of functional regulation of the ATP receptor channel P2X2

(2009) Yoshihiro Kubo et al.   JOURNAL OF PHYSIOLOGY-LONDON

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE