Neurogenin3 Cooperates with Foxa2 to Autoactivate Its Own Expression

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation

(2012) H. P. Shih et al.   DEVELOPMENT

RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors

(2012) N. Thompson et al.   MOLECULAR AND CELLULAR BIOLOGY

Plasticity of Adult Human Pancreatic Duct Cells by Neurogenin3-Mediated Reprogramming

(2012) Nathalie Swales et al.   PLoS One

Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development

(2011) Anthony Beucher et al.   DEVELOPMENTAL BIOLOGY

Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3

(2011) O. Rubio-Cabezas et al.   DIABETES

The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice

(2011) Y. Yang et al.   DIABETOLOGIA

Sequence and epigenetic determinants in the regulation of the Math6 gene by Neurogenin3

(2011) Gemma Pujadas et al.   DIFFERENTIATION

H3K4 tri-methylation provides an epigenetic signature of active enhancers

(2011) Aleksandra Pekowska et al.   EMBO JOURNAL

Pioneer transcription factors: establishing competence for gene expression

(2011) K. S. Zaret et al.   GENES & DEVELOPMENT

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

(2011) A. A. Serandour et al.   GENOME RESEARCH

Neonatal Diabetes and Congenital Malabsorptive Diarrhea Attributable to a Novel Mutation in the Human Neurogenin-3 Gene Coding Sequence

(2011) Sara E. Pinney et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Construction and Modelling of an Inducible Positive Feedback Loop Stably Integrated in a Mammalian Cell-Line

(2011) Velia Siciliano et al.   PLoS Computational Biology

Foxa1 and Foxa2 Maintain the Metabolic and Secretory Features of the Mature β-Cell

(2010) Nan Gao et al.   MOLECULAR ENDOCRINOLOGY

Combinatorial Gene Regulation Using Auto-Regulation

(2010) Rutger Hermsen et al.   PLoS Computational Biology

Transcriptional autoregulation in development

(2009) Stephen T. Crews et al.   CURRENT BIOLOGY

Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas

(2009) Sui Wang et al.   DEVELOPMENTAL BIOLOGY

Chronology of Islet Differentiation Revealed By Temporal Cell Labeling

(2009) T. Miyatsuka et al.   DIABETES

Gene Therapy with Neurogenin 3 and Betacellulin Reverses Major Metabolic Problems in Insulin-Deficient Diabetic Mice

(2009) Vijay Yechoor et al.   ENDOCRINOLOGY

The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice

(2009) Jennifer M. Oliver-Krasinski et al.   JOURNAL OF CLINICAL INVESTIGATION

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

(2009) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation

(2008) Sui Wang et al.   DEVELOPMENTAL BIOLOGY

Biphasic Ngn3 expression in the developing pancreas

(2008) Alethia Villasenor et al.   DEVELOPMENTAL DYNAMICS

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development

(2008) N. Gao et al.   GENES & DEVELOPMENT

Transcriptional Autoregulation Controls Pancreatic Ptf1a Expression during Development and Adulthood

(2008) T. Masui et al.   MOLECULAR AND CELLULAR BIOLOGY