Aurora B Is Regulated by the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (MAPK/ERK) Signaling Pathway and Is a Valuable Potential Target in Melanoma Cells

PTEN Loss Confers BRAF Inhibitor Resistance to Melanoma Cells through the Suppression of BIM Expression

(2011) K. H. T. Paraiso et al.   CANCER RESEARCH

The Aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe

(2011) Yungan Tao et al.   CELL CYCLE

Senescent cells develop a PARP-1 and nuclear factor- B-associated secretome (PNAS)

(2011) M. Ohanna et al.   GENES & DEVELOPMENT

EGFR in melanoma: clinical significance and potential therapeutic target

(2011) Barbara Boone et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC

(2010) Zhong-Zhe Lin et al.   BMC CANCER

Oncogenic B-RafV600E Induces Spindle Abnormalities, Supernumerary Centrosomes, and Aneuploidy in Human Melanocytic Cells

(2010) Y. Cui et al.   CANCER RESEARCH

Microphthalmia-Associated Transcription Factor Controls the DNA Damage Response and a Lineage-Specific Senescence Program in Melanomas

(2010) Sandy Giuliano et al.   CANCER RESEARCH

Response of experimental malignant melanoma models to the pan-Aurora kinase inhibitor VE-465

(2010) Christine Pirker et al.   EXPERIMENTAL DERMATOLOGY

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer

(2010) Christopher P Gully et al.   Molecular Cancer

PF-03814735, an Orally Bioavailable Small Molecule Aurora Kinase Inhibitor for Cancer Therapy

(2010) Jitesh P. Jani et al.   MOLECULAR CANCER THERAPEUTICS

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

(2010) Poulikos I. Poulikakos et al.   NATURE

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

(2010) Georgia Hatzivassiliou et al.   NATURE

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

(2010) Ramin Nazarian et al.   NATURE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss of c-Met Disrupts Gene Expression Program Required for G2/M Progression during Liver Regeneration in Mice

(2010) Valentina M. Factor et al.   PLoS One

SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo

(2009) Jennifer P. Arbitrario et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality

(2008) Yasunari Yamanaka et al.   MECHANISMS OF DEVELOPMENT

EWS-Fli1 Up-Regulates Expression of the Aurora A and Aurora B Kinases

(2008) K. Wakahara et al.   MOLECULAR CANCER RESEARCH