Expansion of Protein Farnesyltransferase Specificity Using “Tunable” Active Site Interactions

Multispecific Recognition: Mechanism, Evolution, and Design

(2011) Ariel Erijman et al.   BIOCHEMISTRY

Identification of a Novel Class of Farnesylation Targets by Structure-Based Modeling of Binding Specificity

(2011) Nir London et al.   PLoS Computational Biology

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Engineering Thrombin for Selective Specificity toward Protein C and PAR1

(2010) Francesca Marino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Tagging-via-substrate Approach to Detect the Farnesylated Proteome Using Two-dimensional Electrophoresis Coupled with Western Blotting

(2010) Fredrick O. Onono et al.   MOLECULAR & CELLULAR PROTEOMICS

Context-Dependent Substrate Recognition by Protein Farnesyltransferase†

(2009) James L. Hougland et al.   BIOCHEMISTRY

Synthesis and screening of a CaaL peptide library versus FTase reveals a surprising number of substrates

(2009) Amanda J. Krzysiak et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of Novel Peptide Substrates for Protein Farnesyltransferase Reveals Two Substrate Classes with Distinct Sequence Selectivities

(2009) James L. Hougland et al.   JOURNAL OF MOLECULAR BIOLOGY

Analysis of the eukaryotic prenylome by isoprenoid affinity tagging

(2009) Uyen T T Nguyen et al.   Nature Chemical Biology

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling

(2009) A B Hanker et al.   ONCOGENE

Quantitative determination of farnesyl and geranylgeranyl diphosphate levels in mammalian tissue

(2008) Huaxiang Tong et al.   ANALYTICAL BIOCHEMISTRY

Rho Family GTPase Modification and Dependence on CAAXMotif-signaled Posttranslational Modification

(2008) Patrick J. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Highly active and selective endopeptidases with programmed substrate specificities

(2008) Navin Varadarajan et al.   Nature Chemical Biology