Inhibition of Neddylation Represses Lipopolysaccharide-induced Proinflammatory Cytokine Production in Macrophage Cells
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of Neddylation Represses Lipopolysaccharide-induced Proinflammatory Cytokine Production in Macrophage Cells
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 42, Pages 35756-35767
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-08-28
DOI
10.1074/jbc.m112.397703
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Induction of p21-Dependent Senescence by an NAE Inhibitor, MLN4924, as a Mechanism of Growth Suppression
- (2015) Lijun Jia et al. NEOPLASIA
- Role and function of macrophages in the metabolic syndrome
- (2012) Prerna Bhargava et al. BIOCHEMICAL JOURNAL
- NEDD8 Pathways in Cancer, Sine Quibus Non
- (2011) Ian R. Watson et al. CANCER CELL
- Radiosensitization of Human Pancreatic Cancer Cells by MLN4924, an Investigational NEDD8-Activating Enzyme Inhibitor
- (2011) D. Wei et al. CANCER RESEARCH
- Targeting protein neddylation: a novel therapeutic strategy for the treatment of cancer
- (2011) Meng Wang et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma
- (2011) Tom Luedde et al. Nature Reviews Gastroenterology & Hepatology
- Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity
- (2011) Julie L. Lukkarila et al. ACS Medicinal Chemistry Letters
- A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries
- (2011) Sheila Fisher et al. GENOME BIOLOGY
- MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF- B-dependent lymphoma
- (2010) M. A. Milhollen et al. BLOOD
- Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia
- (2010) R. T. Swords et al. BLOOD
- NEDD8-Targeting Drug MLN4924 Elicits DNA Rereplication by Stabilizing Cdt1 in S Phase, Triggering Checkpoint Activation, Apoptosis, and Senescence in Cancer Cells
- (2010) J. J. Lin et al. CANCER RESEARCH
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- Deciphering the complexity of Toll-like receptor signaling
- (2010) Renato Ostuni et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- DAMPening Inflammation by Modulating TLR Signalling
- (2010) A. M. Piccinini et al. MEDIATORS OF INFLAMMATION
- The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
- (2010) Agnes E. Coutinho et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ
- (2010) James E. Brownell et al. MOLECULAR CELL
- NF-κB-mediated expression of MAPK phosphatase-1 is an early step in desensitization to TLR ligands in enterocytes
- (2010) J Wang et al. Mucosal Immunology
- The tumor microenvironment in hepatocellular carcinoma: Current status and therapeutic targets
- (2010) Ju Dong Yang et al. SEMINARS IN CANCER BIOLOGY
- Macrophages: Master Regulators of Inflammation and Fibrosis
- (2010) Thomas Wynn et al. SEMINARS IN LIVER DISEASE
- Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
- (2010) Wasaporn Chanput et al. Food & Function
- Macrophages and Inflammatory Mediators in Chemical Toxicity: A Battle of Forces
- (2009) Debra L. Laskin CHEMICAL RESEARCH IN TOXICOLOGY
- The roles of TLRs, RLRs and NLRs in pathogen recognition
- (2009) T. Kawai et al. INTERNATIONAL IMMUNOLOGY
- An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
- (2009) Teresa A. Soucy et al. NATURE
- Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol
- (2009) Franziska B. Mullauer et al. PLoS One
- MG132 proteasome inhibitor modulates proinflammatory cytokines production and expression of their receptors in U937 cells: involvement of nuclear factor-κB and activator protein-1
- (2008) Pablo C. Ortiz-Lazareno et al. IMMUNOLOGY
- Lys63-Linked Polyubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF- B Activation
- (2008) D. B. Conze et al. MOLECULAR AND CELLULAR BIOLOGY
- Molecular mechanisms regulating glucocorticoid sensitivity and resistance
- (2008) Katherine L. Gross et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Minireview: Latest Perspectives on Antiinflammatory Actions of Glucocorticoids
- (2008) Karolien De Bosscher et al. MOLECULAR ENDOCRINOLOGY
- The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling
- (2008) Paul N. Moynagh TRENDS IN IMMUNOLOGY
- The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1
- (2007) Alban Ordureau et al. BIOCHEMICAL JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now