Modification of the DNA Damage Response by Therapeutic CDK4/6 Inhibition
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Modification of the DNA Damage Response by Therapeutic CDK4/6 Inhibition
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 34, Pages 29075-29087
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-06-27
DOI
10.1074/jbc.m112.365494
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1)
- (2011) G K Schwartz et al. BRITISH JOURNAL OF CANCER
- A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells
- (2011) Lars Anders et al. CANCER CELL
- γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization
- (2011) Markus Löbrich et al. CELL CYCLE
- Expression of p16 and Retinoblastoma Determines Response to CDK4/6 Inhibition in Ovarian Cancer
- (2011) Gottfried E. Konecny et al. CLINICAL CANCER RESEARCH
- Newly identified aspects of tumor suppression by RB
- (2011) P. Viatour et al. Disease Models & Mechanisms
- Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer
- (2011) C. Thangavel et al. ENDOCRINE-RELATED CANCER
- RB and p53 Cooperate to Prevent Liver Tumorigenesis in Response to Tissue Damage
- (2011) A. Kathleen McClendon et al. GASTROENTEROLOGY
- Pharmacologic Inhibition of Cyclin-Dependent Kinases 4 and 6 Arrests the Growth of Glioblastoma Multiforme Intracranial Xenografts
- (2010) K. Michaud et al. CANCER RESEARCH
- RB-pathway disruption in breast cancer
- (2010) Adam Ertel et al. CELL CYCLE
- New Insights into Checkpoint Kinase 1 in the DNA Damage Response Signaling Network
- (2010) Y. Dai et al. CLINICAL CANCER RESEARCH
- Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure
- (2010) J L Dean et al. ONCOGENE
- Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM
- (2010) W. R. Wiedemeyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells
- (2010) Farjana Fattah et al. PLoS Genetics
- High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy
- (2009) D. Trere et al. ANNALS OF ONCOLOGY
- DNA Repair in Mammalian Cells
- (2009) B. Pardo et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability
- (2009) David Schild et al. NUCLEIC ACIDS RESEARCH
- Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
- (2008) Peter J Campbell et al. NATURE GENETICS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now