The Increase inO-LinkedN-Acetylglucosamine Protein Modification Stimulates Chondrogenic Differentiation Bothin Vitroandin Vivo

Extensive Crosstalk between O-GlcNAcylation and Phosphorylation Regulates Akt Signaling

(2012) Shuai Wang et al.   PLoS One

O-linked β-N-acetylglucosamine supports p38 MAPK activation by high glucose in glomerular mesangial cells

(2011) Howard Goldberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

dbOGAP - An Integrated Bioinformatics Resource for Protein O-GlcNAcylation

(2011) Jinlian Wang et al.   BMC BIOINFORMATICS

Protein O-GlcNAcylation regulates Drosophila growth through the insulin signaling pathway

(2011) Sujin Park et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Swim-exercised mice show a decreased level of protein O-GlcNAcylation and expression of O-GlcNAc transferase in heart

(2011) Darrell D. Belke   JOURNAL OF APPLIED PHYSIOLOGY

Suppression of Glutamine:Fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes

(2011) Tusty-Jiuan Hsieh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure

(2011) Ida G. Lunde et al.   PHYSIOLOGICAL GENOMICS

The mechanism of ascorbic acid-induced differentiation of ATDC5 chondrogenic cells

(2010) Tecla M. Temu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions

(2010) Atsushi Fukai et al.   ARTHRITIS AND RHEUMATISM

Characteristic increase in nucleocytoplasmic protein glycosylation by O -GlcNAc in 3T3-L1 adipocyte differentiation

(2010) Katsunori Ishihara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elevation of Global O-GlcNAc in Rodents Using a Selective O-GlcNAcase Inhibitor Does Not Cause Insulin Resistance or Perturb Glucohomeostasis

(2010) Matthew S. Macauley et al.   CHEMISTRY & BIOLOGY

O-Linked β-N-acetylglucosamine (O-GlcNAc) Regulates Stress-induced Heat Shock Protein Expression in a GSK-3β-dependent Manner

(2010) Zahra Kazemi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of adiponectin on ATDC5 proliferation, differentiation and signaling pathways

(2010) T. Delessa Challa et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

244 OSTEOARTHRITIS LEADS TO INCREASED LEVELS OF PROTEIN O-LINKED N-ACETYLGLUCOSAMINE IN THE CARTILAGE

(2010) L. Tardío et al.   OSTEOARTHRITIS AND CARTILAGE

O-GlcNAc signaling: a metabolic link between diabetes and cancer?

(2010) C. Slawson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders

(2010) Rita Dreier   ARTHRITIS RESEARCH & THERAPY

Dysregulation of the nutrient/stress sensor O-GlcNAcylation is involved in the etiology of cardiovascular disorders, type-2 diabetes and Alzheimer's disease

(2009) Tony Lefebvre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase

(2009) Matthew S. Macauley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine

(2009) John A. Hanover et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of Insulin Receptor Substrate 1 (IRS-1)/AKT Kinase-mediated Insulin Signaling byO-Linked β-N-Acetylglucosamine in 3T3-L1 Adipocytes

(2009) Stephen A. Whelan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Calcium/Calmodulin-dependent Kinase IV byO-GlcNAc Modification

(2009) Wagner B. Dias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signalling molecules and growth factors for tissue engineering of cartilage-what can we learn from the growth plate?

(2009) Christoph Brochhausen et al.   Journal of Tissue Engineering and Regenerative Medicine

Regulation of cartilage formation and maturation by mitogen-activated protein kinase signaling

(2008) Brent E. Bobick et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation

(2008) Veronica Ulici et al.   BMC DEVELOPMENTAL BIOLOGY

Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment

(2008) Rayyan A. Kayal et al.   BONE

O-GlcNAc-glycosylation of β-catenin regulates its nuclear localization and transcriptional activity

(2008) Ria Sayat et al.   EXPERIMENTAL CELL RESEARCH

Glucose Deprivation StimulatesO-GlcNAc Modification of Proteins through Up-regulation ofO-LinkedN-Acetylglucosaminyltransferase

(2008) Rodrick P. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevation of GlobalO-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition ofO-GlcNAcase Does Not Induce Insulin Resistance

(2008) Matthew S. Macauley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In VivoModulation ofO-GlcNAc Levels Regulates Hippocampal Synaptic Plasticity through Interplay with Phosphorylation

(2008) Melanie K. Tallent et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes

(2008) Yosuke Kawasaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

(2008) Xiaoyong Yang et al.   NATURE

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

(2008) Scott A Yuzwa et al.   Nature Chemical Biology

Long-term NSAID treatment directly decreases COX-2 and mPGES-1 production in the articular cartilage of patients with osteoarthritis

(2008) M.A. Álvarez-Soria et al.   OSTEOARTHRITIS AND CARTILAGE