Mammalian Target of Rapamycin (mTOR) Signaling Network in Skeletal Myogenesis

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Yin Yang 1 Deficiency in Skeletal Muscle Protects against Rapamycin-Induced Diabetic-like Symptoms through Activation of Insulin/IGF Signaling

(2012) Sharon M. Blättler et al.   Cell Metabolism

Kinome-wide Selectivity Profiling of ATP-competitive Mammalian Target of Rapamycin (mTOR) Inhibitors and Characterization of Their Binding Kinetics

(2012) Qingsong Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase D and mTORC1: Nutrients Are What Bring Them Together

(2012) B. M. Wiczer et al.   Science Signaling

Transcriptional Control of Cellular Metabolism by mTOR Signaling

(2011) J. L. Yecies et al.   CANCER RESEARCH

mTOR signaling: PLD takes center stage

(2011) Yuting Sun et al.   CELL CYCLE

mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes

(2011) Chi Kwan Tsang et al.   CELL CYCLE

MicroRNAs in skeletal myogenesis

(2011) Yejing Ge et al.   CELL CYCLE

mTOR complex 2 signaling and functions

(2011) Won Jun Oh et al.   CELL CYCLE

mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry

(2011) N. Dai et al.   GENES & DEVELOPMENT

Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle

(2011) Troy A. Hornberger   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phospholipase D Mediates Nutrient Input to Mammalian Target of Rapamycin Complex 1 (mTORC1)

(2011) Limei Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase D Regulates Myogenic Differentiation through the Activation of Both mTORC1 and mTORC2 Complexes

(2011) Rami Jaafar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Raptor and Rheb Negatively Regulate Skeletal Myogenesis through Suppression of Insulin Receptor Substrate 1 (IRS1)

(2011) Yejing Ge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Class III PI-3-kinase activates phospholipase D in an amino acid–sensing mTORC1 pathway

(2011) Mee-Sup Yoon et al.   JOURNAL OF CELL BIOLOGY

IGF-II is regulated by microRNA-125b in skeletal myogenesis

(2011) Yejing Ge et al.   JOURNAL OF CELL BIOLOGY

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

(2011) Y. Yu et al.   SCIENCE

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

(2011) P. P. Hsu et al.   SCIENCE

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

(2011) Jessica J. Howell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Signaling pathways perturbing muscle mass

(2010) David J Glass   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis

(2010) Yuting Sun et al.   JOURNAL OF CELL BIOLOGY

A Phosphatidylinositol 3-Kinase/Protein Kinase B-independent Activation of Mammalian Target of Rapamycin Signaling Is Sufficient to Induce Skeletal Muscle Hypertrophy

(2010) Craig A. Goodman et al.   MOLECULAR BIOLOGY OF THE CELL

mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1

(2010) T. Kantidakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms

(2009) Yejing Ge et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

(2009) Anne Ulrike Trendelenburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

(2009) Valérie Risson et al.   JOURNAL OF CELL BIOLOGY

Regulation of Myoblast Differentiation by the Nuclear Envelope Protein NET39

(2009) G.-H. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1

(2009) C. C. Dibble et al.   MOLECULAR AND CELLULAR BIOLOGY

mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling

(2009) L.-A. Julien et al.   MOLECULAR AND CELLULAR BIOLOGY

The mTORC2 Complex Regulates Terminal Differentiation of C2C12 Myoblasts

(2009) L. Shu et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Amino acid regulation of TOR complex 1

(2008) Joseph Avruch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Rictor and Integrin-Linked Kinase Interact and Regulate Akt Phosphorylation and Cancer Cell Survival

(2008) P. C. McDonald et al.   CANCER RESEARCH

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

(2008) C. Florian Bentzinger et al.   Cell Metabolism

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

(2008) Valeria Facchinetti et al.   EMBO JOURNAL

Differential Antagonism of Activin, Myostatin and Growth and Differentiation Factor 11 by Wild-Type and Mutant Follistatin

(2008) Alan L. Schneyer et al.   ENDOCRINOLOGY

microRNAs and muscle disorders

(2008) J.-F. Chen et al.   JOURNAL OF CELL SCIENCE

PLD regulates myoblast differentiation through the mTOR-IGF2 pathway

(2008) M.-S. Yoon et al.   JOURNAL OF CELL SCIENCE

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY

Forkhead Box Protein O1 Negatively Regulates Skeletal Myocyte Differentiation through Degradation of Mammalian Target of Rapamycin Pathway Components

(2007) Ai-Luen Wu et al.   ENDOCRINOLOGY