Structural Link between γ-Aminobutyric Acid Type A (GABAA) Receptor Agonist Binding Site and Inner β-Sheet Governs Channel Activation and Allosteric Drug Modulation

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Linking the Acetylcholine Receptor-Channel Agonist-Binding Sites with the Gate

(2010) David J. Cadugan et al.   BIOPHYSICAL JOURNAL

Photochemical Proteolysis of an Unstructured Linker of the GABAAR Extracellular Domain Prevents GABA but Not Pentobarbital Activation

(2010) A. P. Hanek et al.   MOLECULAR PHARMACOLOGY

Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor

(2010) Feyza Sancar et al.   NEUROPHARMACOLOGY

An Epilepsy-Related Region in the GABAA Receptor Mediates Long-Distance Effects on GABA and Benzodiazepine Binding Sites

(2009) M. P. Goldschen-Ohm et al.   MOLECULAR PHARMACOLOGY

A Hydrogen Bond in Loop A Is Critical for the Binding and Function of the 5-HT3Receptor†

(2008) Kerry L. Price et al.   BIOCHEMISTRY

γ-Aminobutyric Acid (GABA) and Pentobarbital Induce Different Conformational Rearrangements in the GABAAReceptor α1and β2Pre-M1 Regions

(2008) Jose Mercado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Agonist- and competitive antagonist-induced movement of loop 5 on the α subunit of the neuronal α4β4 nicotinic acetylcholine receptor

(2008) Alexandre Mourot et al.   JOURNAL OF NEUROCHEMISTRY

Individually Monitoring Ligand-Induced Changes in the Structure of the GABAA Receptor at Benzodiazepine Binding Site and Non-Binding-Site Interfaces

(2008) L. M. Sharkey et al.   MOLECULAR PHARMACOLOGY

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Mapping a molecular link between allosteric inhibition and activation of the glycine receptor

(2008) Paul S Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of action of benzodiazepines on GABAA receptors

(2006) Claudia Campo-Soria et al.   BRITISH JOURNAL OF PHARMACOLOGY