Methionine Oxidation Perturbs the Structural Core of the Prion Protein and Suggests a Generic Misfolding Pathway
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Methionine Oxidation Perturbs the Structural Core of the Prion Protein and Suggests a Generic Misfolding Pathway
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 34, Pages 28263-28275
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-06-01
DOI
10.1074/jbc.m112.354779
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metal ions and amyloid fiber formation in neurodegenerative diseases. Copper, zinc and iron in Alzheimer's, Parkinson's and prion diseases
- (2012) John H. Viles COORDINATION CHEMISTRY REVIEWS
- Methionine Oxidation of Sup35 Protein Induces Formation of the [PSI+] Prion in a Yeast Peroxiredoxin Mutant
- (2011) Theodora C. Sideri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Copper(II)-Induced Secondary Structure Changes and Reduced Folding Stability of the Prion Protein
- (2011) Nadine D. Younan et al. JOURNAL OF MOLECULAR BIOLOGY
- Copper Redox Cycling in the Prion Protein Depends Critically on Binding Mode
- (2011) Lin Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Methionine-Oxidized Amyloid Fibrils Are Poor Substrates for Human Methionine Sulfoxide Reductases A and B2
- (2010) Katrina J. Binger et al. BIOCHEMISTRY
- Detailed Biophysical Characterization of the Acid-Induced PrPcto PrPβConversion Process
- (2010) Trent C. Bjorndahl et al. BIOCHEMISTRY
- Substoichiometric Levels of Cu2+Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer Disease
- (2010) Claire J. Sarell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oxidation of Helix-3 Methionines Precedes the Formation of PK Resistant PrPSc
- (2010) Tamar Canello et al. PLoS Pathogens
- Evaluation of Copper2+Affinities for the Prion Protein
- (2009) Rebecca C. Nadal et al. BIOCHEMISTRY
- Methionine Sulfoxides on Prion Protein Helix-3 Switch on the α-Fold Destabilization Required for Conversion
- (2009) Giorgio Colombo et al. PLoS One
- Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein
- (2009) C. Wolschner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamics of a truncated prion protein, PrP(113-231), from15N NMR relaxation: Order parameters calculated and slow conformational fluctuations localized to a distinct region
- (2009) Denis B. D. O'Sullivan et al. PROTEIN SCIENCE
- Copper and the structural biology of the prion protein
- (2008) John H. Viles et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Amyloid β−Cu2+Complexes in both Monomeric and Fibrillar Forms Do Not Generate H2O2Catalytically but Quench Hydroxyl Radicals†
- (2008) Rebecca C. Nadal et al. BIOCHEMISTRY
- Methionine Sulfoxides on PrPSc: A Prion-Specific Covalent Signature†
- (2008) Tamar Canello et al. BIOCHEMISTRY
- A manganese-superoxide dismutase/catalase mimetic extends survival in a mouse model of human prion disease
- (2008) Marcus W. Brazier et al. FREE RADICAL BIOLOGY AND MEDICINE
- Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease
- (2008) Reinald Pamplona et al. FREE RADICAL BIOLOGY AND MEDICINE
- Prion Protein Amyloid Formation under Native-like Conditions Involves Refolding of the C-terminal α-Helical Domain
- (2008) Nathan J. Cobb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genes contributing to prion pathogenesis
- (2008) G. Tamguney et al. JOURNAL OF GENERAL VIROLOGY
- Extrinsic Fluorescent Dyes as Tools for Protein Characterization
- (2008) Andrea Hawe et al. PHARMACEUTICAL RESEARCH
- Conformational pH dependence of intermediate states during oligomerization of the human prion protein
- (2008) Remo Gerber et al. PROTEIN SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now