Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

Mannose-Binding Lectin (MBL)-Associated Serine Protease (MASP)-1 Contributes to Activation of the Lectin Complement Pathway

(2014) Minoru Takahashi et al.   JOURNAL OF IMMUNOLOGY

High Affinity Small Protein Inhibitors of Human Chymotrypsin C (CTRC) Selected by Phage Display Reveal Unusual Preference for P4′ Acidic Residues

(2011) András Szabó et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

(2011) W. J. Schwaeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Catalytic Aspartate Is Protonated in the Michaelis Complex Formed between Trypsin and anin VitroEvolved Substrate-like Inhibitor

(2010) Weixiao Yuan Wahlgren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Mannose-binding Lectin/Ficolin-associated Protein Is Highly Expressed in Heart and Skeletal Muscle Tissues and Inhibits Complement Activation

(2010) Mikkel-Ole Skjoedt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Inhibition of the Lectin Pathway of Complement with Phage Display Selected Peptides against Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 and -2: Significant Contribution of MASP-1 to Lectin Pathway Activation

(2010) A. Kocsis et al.   JOURNAL OF IMMUNOLOGY

Collectin 11 (CL-11, CL-K1) Is a MASP-1/3-Associated Plasma Collectin with Microbial-Binding Activity

(2010) S. Hansen et al.   JOURNAL OF IMMUNOLOGY

Identification of Complin, a Novel Complement Inhibitor that Targets Complement Proteins Factor B and C2

(2010) A. P. Kadam et al.   JOURNAL OF IMMUNOLOGY

Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency

(2010) Hongchang Qu et al.   MOLECULAR IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Complement factor D, a novel serine protease

(2010) John E. Volanakis et al.   PROTEIN SCIENCE

C1 inhibitor, a multi-functional serine protease inhibitor

(2010) Fengxin Lu et al.   THROMBOSIS AND HAEMOSTASIS

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation

(2009) S. E. Degn et al.   JOURNAL OF IMMUNOLOGY

MASP-1, a Promiscuous Complement Protease: Structure of Its Catalytic Region Reveals the Basis of Its Broad Specificity

(2009) J. Dobo et al.   JOURNAL OF IMMUNOLOGY

Complement Protease MASP-1 Activates Human Endothelial Cells: PAR4 Activation Is a Link between Complement and Endothelial Function

(2009) M. Megyeri et al.   JOURNAL OF IMMUNOLOGY

Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions

(2009) Péter Gál et al.   MOLECULAR IMMUNOLOGY

Structure ofLocusta migratoriaprotease inhibitor 3 (LMPI-3) in complex withFusarium oxysporumtrypsin

(2008) Philippe Leone et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Pacifastin-related peptides: Structural and functional characteristics of a family of serine peptidase inhibitors

(2008) Bert Breugelmans et al.   PEPTIDES