Ciliary Neurotrophic Factor Protects Mice Against Streptozotocin-induced Type 1 Diabetes through SOCS3

Ciliary neurotrophic factor (CNTF) protects non-obese Swiss mice against type 2 diabetes by increasing beta cell mass and reducing insulin clearance

(2012) L. F. Rezende et al.   DIABETOLOGIA

CNTF protects MIN6 cells against apoptosis induced by Alloxan and IL-1β through downregulation of the AMPK pathway

(2011) Gustavo J. Santos et al.   CELLULAR SIGNALLING

β-cell specific overexpression of suppressor of cytokine signalling-3 does not protect against multiple low dose streptozotocin induced type 1 diabetes in mice

(2011) A. Börjesson et al.   IMMUNOLOGY LETTERS

Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies

(2011) Tom L. Van Belle et al.   PHYSIOLOGICAL REVIEWS

Conditional and specific inhibition of NF-κB in mouse pancreatic β cells prevents cytokine-induced deleterious effects and improves islet survival posttransplant

(2011) Jonathan S. Rink et al.   SURGERY

Cytokine signaling in the human brain capillary endothelial cell line hCMEC/D3

(2010) Elizaveta Fasler-Kan et al.   BRAIN RESEARCH

The induction of STAT1 gene by activating transcription factor 3 contributes to pancreatic β-cell apoptosis and its dysfunction in streptozotocin-treated mice

(2010) Ji Yeon Kim et al.   CELLULAR SIGNALLING

STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation

(2010) Fabrice Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ciliary neurotrophic factor (CNTF) signals through STAT3–SOCS3 pathway and protects rat pancreatic islets from cytokine-induced apoptosis

(2009) Luiz F. Rezende et al.   CYTOKINE

Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase-Dependent Pathway That Is Impaired With Obesity

(2009) G. R. Steinberg et al.   DIABETES

Acute Alcohol Intake Induces SOCS1 and SOCS3 and Inhibits Cytokine-Induced STAT1 and STAT3 Signaling in Human Monocytes

(2008) Oxana Norkina et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effects of systemic administration of ciliary neurotrophic factor on Bax and Bcl-2 proteins in the lumbar spinal cord of neonatal rats after sciatic nerve transection

(2008) A.C.S. Rezende et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

NO-mediated cytotoxicity contributes to multiple low-dose streptozotocin-induced diabetes but not to NOD diabetes

(2008) Hisafumi Yasuda et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection

(2008) S. G. Rønn et al.   DIABETOLOGIA

CNTF: a target therapeutic for obesity-related metabolic disease?

(2008) Vance B. Matthews et al.   JOURNAL OF MOLECULAR MEDICINE-JMM