Curcumin Suppresses Soluble Tau Dimers and Corrects Molecular Chaperone, Synaptic, and Behavioral Deficits in Aged Human Tau Transgenic Mice

Evidence that Non-Fibrillar Tau Causes Pathology Linked to Neurodegeneration and Behavioral Impairments

(2017) Kurt R. Brunden et al.   JOURNAL OF ALZHEIMERS DISEASE

Peroxynitrite-Induced Nitrative and Oxidative Modifications Alter Tau Filament Formation

(2011) Laurel Vana et al.   BIOCHEMISTRY

Safety assessment of a solid lipid curcumin particle preparation: Acute and subchronic toxicity studies

(2011) Paresh Dadhaniya et al.   FOOD AND CHEMICAL TOXICOLOGY

Heat Shock Cognate Protein 70 Regulates Gephyrin Clustering

(2011) P. Machado et al.   JOURNAL OF NEUROSCIENCE

Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

(2011) Silvestre Alavez et al.   NATURE

Towards a Pharmacophore for Amyloid

(2011) Meytal Landau et al.   PLOS BIOLOGY

Preparation and Characterization of Neurotoxic Tau Oligomers

(2010) Cristian A. Lasagna-Reeves et al.   BIOCHEMISTRY

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Safety and Pharmacokinetics of a Solid Lipid Curcumin Particle Formulation in Osteosarcoma Patients and Healthy Volunteers

(2010) Vikram S. Gota et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway

(2010) Philip J. Dolan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsc70 Rapidly Engages Tau after Microtubule Destabilization

(2010) Umesh K. Jinwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin in dendritic spines: connecting dynamics to function

(2010) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Curcumin Labeling of Neuronal Fibrillar Tau Inclusions in Human Brain Samples

(2010) Nina Mohorko et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model

(2010) A. Boutajangout et al.   JOURNAL OF NEUROSCIENCE

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

(2010) John C O'Leary et al.   Molecular Neurodegeneration

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

The proline-rich domain of tau plays a role in interactions with actin

(2009) Hai He et al.   BMC CELL BIOLOGY

The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition

(2009) Chiara Giommarelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs

(2009) A.B. Rocher et al.   EXPERIMENTAL NEUROLOGY

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology

(2009) M. Polydoro et al.   JOURNAL OF NEUROSCIENCE

Molecular dynamics of postsynaptic receptors and scaffold proteins

(2008) Marianne Renner et al.   CURRENT OPINION IN NEUROBIOLOGY

Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer’s disease

(2008) M. Filali et al.   GENES BRAIN AND BEHAVIOR

Spatial memory formation induces recruitment of NMDA receptor and PSD-95 to synaptic lipid rafts

(2008) Ilse Delint-Ramírez et al.   JOURNAL OF NEUROCHEMISTRY

The Potential for -Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy

(2008) M.-M. Mocanu et al.   JOURNAL OF NEUROSCIENCE

Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone

(2008) Mitul Sarkar et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Akt and CHIP coregulate tau degradation through coordinated interactions

(2008) C. A. Dickey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA