A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

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Caspase activation precedes and leads to tangles

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Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons

(2009) Rodrigo A. Quintanilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome-caspase-cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells

(2009) Lisette T. Arnaud et al.   JOURNAL OF NEUROCHEMISTRY

The Cochaperone BAG2 Sweeps Paired Helical Filament- Insoluble Tau from the Microtubule

(2009) D. C. Carrettiero et al.   JOURNAL OF NEUROSCIENCE

Targeting proteins for degradation

(2009) Erin K Schrader et al.   Nature Chemical Biology

The Natively Unfolded Character of Tau and Its Aggregation to Alzheimer-like Paired Helical Filaments†

(2008) Sadasivam Jeganathan et al.   BIOCHEMISTRY

Immortalized cortical neurons expressing caspase-cleaved tau are sensitized to endoplasmic reticulum stress induced cell death

(2008) Tori A. Matthews-Roberson et al.   BRAIN RESEARCH

Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

(2008) Tadanori Hamano et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteins

(2008) Y. Morishima et al.   HUMAN MOLECULAR GENETICS

Autophagy-mediated clearance of aggresomes is not a universal phenomenon

(2008) Esther S.P. Wong et al.   HUMAN MOLECULAR GENETICS

Parkin mediates the degradation-independent ubiquitination of Hsp70

(2008) Darren J. Moore et al.   JOURNAL OF NEUROCHEMISTRY

Misfolded proteins partition between two distinct quality control compartments

(2008) Daniel Kaganovich et al.   NATURE