Elevated Cyclin G2 Expression Intersects with DNA Damage Checkpoint Signaling and Is Required for a Potent G2/M Checkpoint Arrest Response to Doxorubicin

Negative regulation of CHK2 activity by protein phosphatase 2A is modulated by DNA damage

(2011) Alyson K. Freeman et al.   CELL CYCLE

Three independent mechanisms for arrest in G2after ionizing radiation

(2011) Kirsti Solberg Landsverk et al.   CELL CYCLE

Drosophila melanogasterCyclin G coordinates cell growth and cell proliferation

(2011) Floria Faradji et al.   CELL CYCLE

Involvement of DNA-dependent Protein Kinase in Normal Cell Cycle Progression through Mitosis

(2011) Kyung-Jong Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage

(2010) Luigi Carlessi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Moderate variations in CDC25B protein levels modulate the response to DNA damaging agents

(2010) Bernadette Aressy et al.   CELL CYCLE

Centrosomal Chk2 in DNA damage responses and cell cycle progession

(2010) Amnon Golan et al.   CELL CYCLE

The DNA-dependent protein kinase (DNA-PK): More than just a case of making ends meet?

(2010) Richard Hill et al.   CELL CYCLE

UV-induced downregulation of the CDC25B protein in human cells

(2010) Matthieu Lemaire et al.   FEBS LETTERS

Multiple roles of ATM in monitoring and maintaining DNA integrity

(2010) Frederick A. Derheimer et al.   FEBS LETTERS

Multiple roles of the cell cycle inhibitor p21CDKN1A in the DNA damage response

(2010) Ornella Cazzalini et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

The CHK2–BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells

(2010) Ailine Stolz et al.   NATURE CELL BIOLOGY

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

Taking the time to make important decisions: The checkpoint effector kinases Chk1 and Chk2 and the DNA damage response

(2009) Travis H. Stracker et al.   DNA REPAIR

Common mechanisms of PIKK regulation

(2009) Courtney A. Lovejoy et al.   DNA REPAIR

Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells

(2009) Nozomi Tomimatsu et al.   EMBO REPORTS

TATA-binding Protein (TBP)-like Protein Is Engaged in Etoposide-induced Apoptosis through Transcriptional Activation of HumanTAp63Gene

(2009) Yusuke Suenaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The decision to enter mitosis: feedback and redundancy in the mitotic entry network

(2009) Arne Lindqvist et al.   JOURNAL OF CELL BIOLOGY

ATR signaling at a glance

(2009) B. Shiotani et al.   JOURNAL OF CELL SCIENCE

DNA Damage Triggers p21WAF1-dependent Emi1 Down-Regulation That Maintains G2 Arrest

(2009) Jinho Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

(2009) Bunsyo Shiotani et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays

(2009) Yifat Merbl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells

(2009) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitotic phosphatases: from entry guards to exit guides

(2009) Mathieu Bollen et al.   TRENDS IN CELL BIOLOGY

BRCA1 is regulated by Chk2 in response to spindle damage

(2008) Corinne Chabalier-Taste et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Transient Inhibition of ATM Kinase Is Sufficient to Enhance Cellular Sensitivity to Ionizing Radiation

(2008) M. D. Rainey et al.   CANCER RESEARCH

DNA Protein Kinase Dependent G2 Checkpoint Revealed following Knockdown of Ataxia-Telangiectasia Mutated in Human Mammary Epithelial Cells

(2008) S. J.H. Arlander et al.   CANCER RESEARCH

Cyclin G2 Is Degraded through the Ubiquitin-Proteasome Pathway and Mediates the Antiproliferative Effect of Activin Receptor-like Kinase 7

(2008) Guoxiong Xu et al.   MOLECULAR BIOLOGY OF THE CELL